Cellular actin networks exhibit a wide range of sizes, shapes, and architectures tailored to
their biological roles. Once assembled, these filamentous networks are either maintained in …

Actin is a highly conserved and fundamental protein in eukaryotes and participates in a
broad spectrum of cellular functions. Cells maintain a conserved ratio of actin isoforms, with …

Twinfilin is an evolutionarily conserved actin-binding protein initially mischaracterized as a
tyrosine kinase but later recognized as a key regulator of cellular actin dynamics. As a …

Familial hypertrophic cardiomyopathy (HCM) affects. 2% of the world's population and is
inherited in an autosomal dominant manner. Mutations in cardiac α‐actin are the cause in …

Actins are filament-forming, highly-conserved proteins in eukaryotes. They are involved in
essential processes in the cytoplasm and also have nuclear functions. Malaria parasites …

Cytoskeletal dynamics are essential for cellular homeostasis and development for both
metazoans and protozoans. The function of cytoskeletal elements in protozoans can diverge …

The actin cytoskeleton is a ubiquitous feature of eukaryotic cells, yet its complexity varies
across different taxa. In the parasitic protist Trypanosoma brucei, a rudimentary actomyosin …

Diseases caused by Leishmania and Trypanosoma parasites are a major health problem in
tropical countries. Because of their complex life cycle involving both vertebrate and insect …

Leishmaniasis is one of the most important parasitic diseases in the world. Due to the
increasing prevalence of this disease and the increasing reports of glucantime resistance, it …

Diseases caused by Leishmania, and Trypanosoma parasites, such as leishmaniasis and
African slee** sickness, are a major health problem in tropical countries. Due to their …