KNOX genes: versatile regulators of plant development and diversity

A Hay, M Tsiantis - Development, 2010 - journals.biologists.com
Knotted1-like homeobox (KNOX) proteins are homeodomain transcription factors that
maintain an important pluripotent cell population called the shoot apical meristem, which …

[HTML][HTML] Role of Hox genes in stem cell differentiation

A Seifert, DF Werheid, SM Knapp… - World journal of stem …, 2015 - ncbi.nlm.nih.gov
Hox genes are an evolutionary highly conserved gene family. They determine the anterior-
posterior body axis in bilateral organisms and influence the developmental fate of cells …

The theory of facilitated variation

J Gerhart, M Kirschner - Proceedings of the National …, 2007 - National Acad Sciences
This theory concerns the means by which animals generate phenotypic variation from
genetic change. Most anatomical and physiological traits that have evolved since the …

Development and Function of the Drosophila Tracheal System

S Hayashi, T Kondo - Genetics, 2018 - academic.oup.com
The tracheal system of insects is a network of epithelial tubules that functions as a
respiratory organ to supply oxygen to various target organs. Target-derived signaling inputs …

Cellular and molecular insights into Hox protein action

R Rezsohazy, AJ Saurin, C Maurel-Zaffran… - …, 2015 - journals.biologists.com
Hox genes encode homeodomain transcription factors that control morphogenesis and have
established functions in development and evolution. Hox proteins have remained enigmatic …

Enhancer evolution and the origins of morphological novelty

M Rebeiz, M Tsiantis - Current Opinion in Genetics & Development, 2017 - Elsevier
Highlights•Genome-wide and single gene studies have revealed a variety of mechanisms by
which new expression patterns arise.•Studying newly evolved morphologies at the level of …

Homeotic genes: clustering, modularity, and diversity

N Hajirnis, RK Mishra - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Hox genes code for transcription factors and are evolutionarily conserved. They regulate a
plethora of downstream targets to define the anterior-posterior (AP) body axis of a …

Co-option of an ancestral Hox-regulated network underlies a recently evolved morphological novelty

WJ Glassford, WC Johnson, NR Dall, SJ Smith, Y Liu… - Developmental cell, 2015 - cell.com
The evolutionary origins of complex morphological structures such as the vertebrate eye or
insect wing remain one of the greatest mysteries of biology. Recent comparative studies of …

A Mechanistic Link between STM and CUC1 during Arabidopsis Development

SV Spinelli, AP Martin, IL Viola, DH Gonzalez… - Plant …, 2011 - academic.oup.com
The KNOXI transcription factor SHOOT MERISTEMLESS (STM) is required to establish and
maintain the Arabidopsis (Arabidopsis thaliana) apical meristem, yet little is known about its …

Activated STAT regulates growth and induces competitive interactions independently of Myc, Yorkie, Wingless and ribosome biogenesis

AB Rodrigues, T Zoranovic, A Ayala-Camargo… - …, 2012 - journals.biologists.com
Cell competition is a conserved mechanism that regulates organ size and shares properties
with the early stages of cancer. In Drosophila, wing cells with increased Myc or with optimum …