Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases
Autophagy is a lysosome-based degradative process used to recycle obsolete cellular
constituents and eliminate damaged organelles and aggregate-prone proteins. Their …
constituents and eliminate damaged organelles and aggregate-prone proteins. Their …
Natural autophagy modulators in non-communicable diseases: from autophagy mechanisms to therapeutic potential
T Xu, Y Deng, X Yu, M Li, Y Fu - Acta Pharmacologica Sinica, 2024 - nature.com
Non-communicable diseases (NCDs) are defined as a kind of diseases closely related to
bad behaviors and lifestyles, eg, cardiovascular diseases, cancer, and diabetes. Driven by …
bad behaviors and lifestyles, eg, cardiovascular diseases, cancer, and diabetes. Driven by …
ATG9A facilitates the closure of mammalian autophagosomes
Canonical autophagy captures within specialized double-membrane organelles, termed
autophagosomes, an array of cytoplasmic components destined for lysosomal degradation …
autophagosomes, an array of cytoplasmic components destined for lysosomal degradation …
Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function
ATG5 is one of the core autophagy proteins with additional functions such as noncanonical
membrane atg8ylation, which among a growing number of biological outputs includes …
membrane atg8ylation, which among a growing number of biological outputs includes …
[HTML][HTML] Molecular Mechanisms Underlying Initiation and Activation of Autophagy
Z Wei, X Hu, Y Wu, L Zhou, M Zhao, Q Lin - Biomolecules, 2024 - mdpi.com
Autophagy is an important catabolic process to maintain cellular homeostasis and
antagonize cellular stresses. The initiation and activation are two of the most important …
antagonize cellular stresses. The initiation and activation are two of the most important …
ATG9 promotes autophagosome formation through interaction with LC3
P Xu, T Zhang, F Yu, L Guo, Y Yang - Biochemical and Biophysical …, 2025 - Elsevier
The autophagosome is a double-membrane organelle that executes macroautophagy.
Previous studies have shown that the autophagosome formation is driven by autophagy …
Previous studies have shown that the autophagosome formation is driven by autophagy …
[HTML][HTML] Bridge-like lipid transfer protein 3A (BLTP3A) is associated with membranes of the late endocytic pathway and is an effector of CASM
MG Hanna, HOR Cruz, K Fujise, Z Li, M Monetti… - …, 2024 - pmc.ncbi.nlm.nih.gov
Recent studies have identified a family of rod-shaped proteins which includes VPS13 and
ATG2 and are thought to mediate unidirectional lipid transport at intracellular membrane …
ATG2 and are thought to mediate unidirectional lipid transport at intracellular membrane …
The food grade bacterium Lactobacillus helveticus VEL12193 promotes autophagy by releasing membrane vesicles
MA Bringer, J Al Azzaz, B Buteau, L Proukhnitzky… - bioRxiv, 2024 - biorxiv.org
Autophagy-related processes, including canonical macroautophagy, are crucial for
maintaining cellular homeostasis in eukaryotic organisms. Alterations or reduced activity of …
maintaining cellular homeostasis in eukaryotic organisms. Alterations or reduced activity of …
Mechanisms of Autophagy–Lysosome Dysfunction in Neurodegenerative Diseases
D Rubinsztein, R Nixon - 2024 - repository.cam.ac.uk
Autophagy is a lysosome-based degradative process used to recycle obsolete cellular
constituents and eliminate damaged organelles and aggregate-prone proteins. Their post …
constituents and eliminate damaged organelles and aggregate-prone proteins. Their post …
[CITATION][C] Molecular mechanisms and physiological functions of autophagy
F Wilfling, M Graef - Journal of Molecular Biology, 2024 - pure.mpg.de
Molecular Mechanisms and Physiological Functions of Autophagy :: MPG.PuRe English Help
Privacy Policy Disclaimer Include files Advanced SearchBrowse START BASKET (0)Tools Item …
Privacy Policy Disclaimer Include files Advanced SearchBrowse START BASKET (0)Tools Item …