Blood-derived lncRNAs as biomarkers for cancer diagnosis: the Good, the Bad and the Beauty

C Badowski, B He, LX Garmire - NPJ precision oncology, 2022 - nature.com
Cancer ranks as one of the deadliest diseases worldwide. The high mortality rate associated
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …

[HTML][HTML] Long non-coding RNA and RNA-binding protein interactions in cancer: experimental and machine learning approaches

H Shaath, R Vishnubalaji, R Elango… - Seminars in cancer …, 2022 - Elsevier
Understanding the complex and specific roles played by non-coding RNAs (ncRNAs), which
comprise the bulk of the genome, is important for understanding virtually every hallmark of …

NONCODE 2016: an informative and valuable data source of long non-coding RNAs

Y Zhao, H Li, S Fang, Y Kang, W Wu, Y Hao… - Nucleic acids …, 2016 - academic.oup.com
Abstract NONCODE (http://www. bioinfo. org/noncode/) is an interactive database that aims
to present the most complete collection and annotation of non-coding RNAs, especially long …

Interaction and cross-talk between non-coding RNAs

S Yamamura, M Imai-Sumida, Y Tanaka… - Cellular and molecular …, 2018 - Springer
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …

The functional role of long non-coding RNA in human carcinomas

EA Gibb, CJ Brown, WL Lam - Molecular cancer, 2011 - Springer
Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

NPInter v4. 0: an integrated database of ncRNA interactions

X Teng, X Chen, H Xue, Y Tang, P Zhang… - Nucleic acids …, 2020 - academic.oup.com
Noncoding RNAs (ncRNAs) play crucial regulatory roles in a variety of biological circuits. To
document regulatory interactions between ncRNAs and biomolecules, we previously …

NONCODEv4: exploring the world of long non-coding RNA genes

C **e, J Yuan, H Li, M Li, G Zhao, D Bu… - Nucleic acids …, 2014 - academic.oup.com
Abstract NONCODE (http://www. bioinfo. org/noncode/) is an integrated knowledge
database dedicated to non-coding RNAs (excluding tRNAs and rRNAs). Non-coding RNAs …

Predicting RNA-protein interactions using only sequence information

UK Muppirala, VG Honavar, D Dobbs - BMC bioinformatics, 2011 - Springer
Background RNA-protein interactions (RPIs) play important roles in a wide variety of cellular
processes, ranging from transcriptional and post-transcriptional regulation of gene …

[HTML][HTML] Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease

B Hrdlickova, RC de Almeida, Z Borek… - Biochimica et Biophysica …, 2014 - Elsevier
It has been found that the majority of disease-associated genetic variants identified by
genome-wide association studies are located outside of protein-coding regions, where they …

Predicting protein associations with long noncoding RNAs

M Bellucci, F Agostini, M Masin, GG Tartaglia - Nature methods, 2011 - nature.com
To the Editor: Only a small fraction of the human transcriptome (∼ 1%) encodes proteins1,
but a large portion of transcripts is long noncoding RNAs (lncRNAs) and is an unexplored …