Risk factors in the development of stem cell therapy
CA Herberts, MSG Kwa, HPH Hermsen - Journal of translational medicine, 2011 - Springer
Stem cell therapy holds the promise to treat degenerative diseases, cancer and repair of
damaged tissues for which there are currently no or limited therapeutic options. The …
damaged tissues for which there are currently no or limited therapeutic options. The …
Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies
During the past decades, extracellular vesicles (EVs) have emerged as an attractive drug
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
The long-term goal of nuclear transfer or alternative reprogramming approaches is to create
patient-specific donor cells for transplantation therapy, avoiding immunorejection, a major …
patient-specific donor cells for transplantation therapy, avoiding immunorejection, a major …
Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient
N Amariglio, A Hirshberg, BW Scheithauer… - PLoS …, 2009 - journals.plos.org
Background Neural stem cells are currently being investigated as potential therapies for
neurodegenerative diseases, stroke, and trauma. However, concerns have been raised over …
neurodegenerative diseases, stroke, and trauma. However, concerns have been raised over …
[BOOK][B] Everything flows: towards a processual philosophy of biology
DJ Nicholson, J Dupré - 2018 - library.oapen.org
This collection of essays explores the metaphysical thesis that the living world is not
ontologically made up of substantial particles or things, as has often been assumed, but is …
ontologically made up of substantial particles or things, as has often been assumed, but is …
A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential
G Kögler, S Sensken, JA Airey, T Trapp… - The Journal of …, 2004 - rupress.org
Here a new, intrinsically pluripotent, CD45-negative population from human cord blood,
termed unrestricted somatic stem cells (USSCs) is described. This rare population grows …
termed unrestricted somatic stem cells (USSCs) is described. This rare population grows …
Stem cell therapy for human neurodegenerative disorders–how to make it work
Recent progress shows that neurons suitable for transplantation can be generated from
stem cells in culture, and that the adult brain produces new neurons from its own stem cells …
stem cells in culture, and that the adult brain produces new neurons from its own stem cells …
Stem cells in human neurodegenerative disorders—time for clinical translation?
Stem cell–based approaches have received much hype as potential treatments for
neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in …
neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in …
Sustained delivery system for stem cell-derived exosomes
Recent literature has ascribed that the paracrine action of stem cells is mediated by
exosomes. Exosomes are nano-sized extracellular vesicles (30 to 100 nm) of endocytic …
exosomes. Exosomes are nano-sized extracellular vesicles (30 to 100 nm) of endocytic …
Potential risks of bone marrow cell transplantation into infarcted hearts
M Breitbach, T Bostani, W Roell, Y **a… - Blood, The Journal …, 2007 - ashpublications.org
Cellular replacement therapy has emerged as a novel strategy for the treatment of heart
failure. The aim of our study was to determine the fate of injected mesenchymal stem cells …
failure. The aim of our study was to determine the fate of injected mesenchymal stem cells …