Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022‏ - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

Extracellular vesicles and their engineering strategies, delivery systems, and biomedical applications

C Yang, Y Xue, Y Duan, C Mao, M Wan - Journal of Controlled Release, 2024‏ - Elsevier
Extracellular vesicles are nanoscale vesicles that can be secreted by all cell types, are
intracellular in origin and have the same composition as their parent cells, play a key role in …

Unraveling multilayered extracellular vesicles: Speculation on cause

K Broad, SA Walker, I Davidovich… - Journal of …, 2023‏ - Wiley Online Library
Extracellular vesicles (EVs) are cell‐released, heterogenous nanoparticles that play
important roles in (patho) physiological processes through intercellular communication. EVs …

Vasculature organotropism in drug delivery

A Amruta, D Iannotta, SW Cheetham, T Lammers… - Advanced drug delivery …, 2023‏ - Elsevier
Over the past decades, there has been an exponential increase in the development of
preclinical and clinical nanodelivery systems, and recently, an accelerating demand to …

Hyaluronic acid: An overlooked extracellular vesicle contaminant

JP Goncalves, RE Ghebosu, XNS Tan… - Journal of …, 2023‏ - Wiley Online Library
The variable presence of contaminants in extracellular vesicle (EV) samples is one of the
major contributors to a lack of inter‐study reproducibility in the field. Well‐known …

Chemically‐induced lipoprotein breakdown for improved extracellular vesicle purification

D Iannotta, A Lai, S Nair, N Koifman, M Lappas… - Small, 2024‏ - Wiley Online Library
Extracellular vesicles (EVs) are nanosized biomolecular packages involved in intercellular
communication. EVs are released by all cells, making them broadly applicable as …

Scalable Purification, storage, and release of plant-derived nanovesicles for local therapy using nanostructured all-cellulose composite membranes

FW Pratiwi, RT Thomas, M Karzarjeddi… - …, 2024‏ - ACS Publications
Plant-derived nanovesicles such as bilberries nanovesicles (BNVs) show immense promise
as next-generation biotherapeutics and functional food ingredients; however, their isolation …