Superparamagnetic iron oxide nanoparticles (SPION) with appropriate surface chemistry
have been widely used experimentally for numerous in vivo applications such as magnetic …

Iron oxides are chemical compounds which have different polymorphic forms, including γ-
Fe2O3 (maghemite), Fe3O4 (magnetite), and FeO (wustite). Among them, the most studied …

The brain contains more than 100 billion neurons that communicate with each other via
axons for the formation of complex neural networks. The structural map** of such …

The ability to track the distribution and differentiation of progenitor and stem cells by high-
resolution in vivo imaging techniques would have significant clinical and research …

We have developed workflows to align 3D magnetic resonance histology (MRH) of the
mouse brain with light sheet microscopy (LSM) and 3D delineations of the same specimen …

The visualisation of living tissues at microscopic resolution is attracting attention in several
fields. In medicine, the goals are to image healthy and diseased tissue with the aim of …

Results First, we sought to demonstrate that ETR expression correlated with increases in
internalized Tf-MION. For these experiments, we implanted nude mice with both stably …

Invasive “body-opening” autopsy represents the traditional means of postmortem
investigation in humans. However, modern cross-sectional imaging techniques can …

The key elements (Fig 2) to sampling molecular information are (a) the use of special
imaging probes with high specificity,(b) appropriate amplification strategies, and (c) sensitive …

A comprehensive three-dimensional digital atlas database of the C57BL/6J mouse brain
was developed based on magnetic resonance microscopy images acquired on a 17.6-T …