Microvalve-based bioprinting–process, bio-inks and applications

WL Ng, JM Lee, WY Yeong, MW Naing - Biomaterials science, 2017 - pubs.rsc.org
Bioprinting is an emerging research field that has attracted tremendous attention for various
applications; it offers a highly automated, advanced manufacturing platform for the …

Microfabricated biomaterials for engineering 3D tissues

P Zorlutuna, N Annabi, G Camci‐Unal… - Advanced …, 2012 - Wiley Online Library
Mimicking natural tissue structure is crucial for engineered tissues with intended
applications ranging from regenerative medicine to biorobotics. Native tissues are highly …

Spatially and temporally controlled hydrogels for tissue engineering

J Leijten, J Seo, K Yue, G Trujillo-de Santiago… - Materials Science and …, 2017 - Elsevier
Recent years have seen tremendous advances in the field of hydrogel-based biomaterials.
One of the most prominent revolutions in this field has been the integration of elements or …

Advanced cell culture platforms: a growing quest for emulating natural tissues

M Mirbagheri, V Adibnia, BR Hughes… - Materials …, 2019 - pubs.rsc.org
In the body, cells inhabit within a complex three-dimensional (3D) extracellular matrix that
provides physical and chemical signals to regulate the cell fate. Cultured cells in Petri dishes …

[HTML][HTML] The impact of microfluidics in high-throughput drug-screening applications

P De Stefano, E Bianchi, G Dubini - Biomicrofluidics, 2022 - pubs.aip.org
Drug discovery is an expensive and lengthy process. Among the different phases, drug
discovery and preclinical trials play an important role as only 5–10 of all drugs that begin …

Stem cell cultivation in bioreactors

CAV Rodrigues, TG Fernandes, MM Diogo… - Biotechnology …, 2011 - Elsevier
Cell-based therapies have generated great interest in the scientific and medical
communities, and stem cells in particular are very appealing for regenerative medicine, drug …

Biofabrication: an overview of the approaches used for printing of living cells

CJ Ferris, KG Gilmore, GG Wallace… - Applied microbiology …, 2013 - Springer
The development of cell printing is vital for establishing biofabrication approaches as
clinically relevant tools. Achieving this requires bio-inks which must not only be easily …

DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications

E Ueda, FL Geyer, V Nedashkivska, PA Levkin - Lab on a Chip, 2012 - pubs.rsc.org
We describe a one-step method for creating thousands of isolated pico-to microliter-sized
droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid …

Three-dimensional structural niches engineered via two-photon laser polymerization promote stem cell homing

MT Raimondi, SM Eaton, M Laganà, V Aprile… - Acta biomaterialia, 2013 - Elsevier
A strategy to modulate the behavior of stem cells in culture is to mimic structural aspects of
the native cell/extracellular matrix interaction. We applied femtosecond laser two-photon …

[HTML][HTML] Stem cell integrins: implications for ex-vivo culture and cellular therapies

ABJ Prowse, F Chong, PP Gray, TP Munro - Stem cell research, 2011 - Elsevier
Use of stem cells, whether adult or embryonic for clinical applications to treat diseases such
as Parkinson's, macular degeneration or Type I diabetes will require a homogenous …