Natural killer (NK) cells are lymphocytes of the innate immune system. A key feature of NK
cells is their ability to recognize a wide range of cells in distress, particularly tumour cells …

Systemic antiplatelet treatment represents a promising option to improve the therapeutic
outcomes and therapeutic efficacy of chemotherapy and immunotherapy due to the critical …

Immunotherapies have revolutionized the treatment paradigms of various types of cancers.
However, most of these immunomodulatory strategies focus on harnessing adaptive …

Metastasis remains a pivotal characteristic of cancer and is the primary contributor to cancer-
associated mortality. Despite its significance, the mechanisms governing metastasis are not …

According to the widely accepted" three Es" model, the host immune system eliminates
malignant cell precursors and contains microscopic neoplasms in a dynamic equilibrium …

The molecules of Major histocompatibility class I (MHC-I) load peptides and present them on
the cell surface, which provided the immune system with the signal to detect and eliminate …

Nasopharyngeal carcinoma (NPC) is a particular entity of head neck cancer that is generally
regarded as a genetic disease with diverse intertumor and intratumor heterogeneity. This …

Current research has demonstrated that extracellular vesicles (EVs) and circulating tumor
cells (CTCs) are very closely related in the process of distant tumor metastasis. Primary …

Organ-specific metastasis is the primary cause of cancer patient death. The distant
metastasis of tumor cells to specific organs depends on both the intrinsic characteristics of …

Metastasis, the spread of cancer from a primary site to distant organs, is an important
challenge in oncology. This Review explores the complexities of immune escape …