Erythrocyte metabolism

PN Chatzinikolaou, NV Margaritelis… - Acta …, 2024‏ - Wiley Online Library
Our aim is to present an updated overview of the erythrocyte metabolism highlighting its
richness and complexity. We have manually collected and connected the available …

Evidence-based sports supplements: A redox analysis

NV Margaritelis, JN Cobley, GG Nastos… - Free Radical Biology …, 2024‏ - Elsevier
Despite the overwhelming number of sports supplements on the market, only seven are
currently recognized as effective. Biological functions are largely regulated through redox …

[HTML][HTML] In-depth characterization revealed polymer type and chemical content specific effects of microplastic on Dreissena bugensis

J Brehm, MV Wilde, L Reiche, LC Leitner… - Journal of Hazardous …, 2022‏ - Elsevier
In aquatic ecosystems, filter feeders like mussels are particularly vulnerable to microplastics
(MP). However, little is known about how the polymer type and the associated properties …

[HTML][HTML] Glucose 6-P dehydrogenase—an antioxidant enzyme with regulatory functions in skeletal muscle during exercise

E García-Domínguez, A Carretero, A Viña-Almunia… - Cells, 2022‏ - mdpi.com
Hypomorphic Glucose 6-P dehydrogenase (G6PD) alleles, which cause G6PD deficiency,
affect around one in twenty people worldwide. The high incidence of G6PD deficiency may …

[HTML][HTML] A translational in vivo and in vitro metabolomic study reveals altered metabolic pathways in red blood cells of type 2 diabetes

M Palomino-Schätzlein, R Lamas-Domingo… - Journal of clinical …, 2020‏ - mdpi.com
Clinical parameters used in type 2 diabetes mellitus (T2D) diagnosis and monitoring such as
glycosylated haemoglobin (HbA1c) are often unable to capture important information related …

Increased exercise tolerance in humanized G6PD-deficient mice

FI Cendali, C Lisk, M Dzieciatkowska… - Blood …, 2025‏ - ashpublications.org
Abstract Glucose-6-phosphate dehydrogenase (G6PD) deficiency affects 500 million people
globally, affecting red blood cell (RBC) antioxidant pathways and increasing susceptibility to …

The redox signal: A physiological perspective

NV Margaritelis, PN Chatzinikolaou… - IUBMB …, 2022‏ - Wiley Online Library
A signal in biology is any kind of coded message sent from one place in an organism to
another place. Biology is rich in claims that reactive oxygen and nitrogen species transmit …

Delineation of the Role of G6PD in Alzheimer's Disease and Potential Enhancement through Microfluidic and Nanoparticle Approaches

OA Sharallah, NK Poddar, OA Alwadan - Ageing Research Reviews, 2024‏ - Elsevier
Alzheimer's disease (AD) is a neurodegenerative pathologic entity characterized by the
abnormal presence of tau and macromolecular Aβ deposition that leads to the degeneration …

[HTML][HTML] Antioxidant supplements versus health benefits of brief/intermittent exposure to potentially toxic physical or chemical agents

R Franco, B Casanovas, J Camps, G Navarro… - Current issues in …, 2021‏ - mdpi.com
Although antioxidants can act locally to react with an oxidant, oral administration of
“antioxidants” is quite useless in treating oxidative stress in tissues. Furthermore, it does not …

Oxygen transport: a redox O2dyssey

PN Chatzinikolaou, NV Margaritelis… - Oxidative Eustress in …, 2022‏ - taylorfrancis.com
Oxygen, a stable di-radical, is critical for aerobic life, and a mismatch between its supply and
demand during exercise decreases performance and precipitates fatigue. In this chapter, we …