Low drug loading and instability in blood circulation are two key challenges that impede the
successful clinical translation of nanomedicine, as they result in only marginal therapeutic …

The properties of the base acridine orange (AOB) in n-heptane/AOT/water reverse micelles
were investigated by using absorption, fluorescence, and single photon counting …

Molecular dynamics simulations were carried out on several systems of caffeine interacting
with simple sugars. These included a single caffeine molecule in a 3 m solution of α-d …

Knowledge of the physical chemistry of small molecules complexation (the hetero-
association) in aqueous solution is increasingly important in view of the rapidly emerging …

The self-association of the antitumour drug, novatrone, NOV (mitoxantrone) and its hetero-
association with caffeine (CAF) have been investigated by 1D and 2D 500 MHz 1H NMR …

Vibrational spectra and molecular structure of anhydrous caffeine have been systematically
investigated by second order Moller–Plesset (MP2) perturbation theory and density …

Photophysical properties of cationic Acridine Orange (AO) have been studied in different
micellar environments [anionic SDS (sodium dodecyl sulfate), nonionic TX (TritonX-100) …

The present review discusses the current state-of-the-art in building models enabling the
description of non-covalent equilibrium complexation of different types of molecules in …

It is suggested that the widely reported biological synergism of a mixture of DNA-targeting
aromatic drug molecules both in vivo and in vitro can be explained, in part, at the molecular …

Ionic hydrogen bond (IHB) interactions, resulting from the association of ammonia and the
two protonated methylxanthine derivatives, caffeine and theophylline, have been …