Oligonucleotide therapies: the past and the present

KE Lundin, O Gissberg, CIE Smith - Human gene therapy, 2015 - liebertpub.com
In this review we address the development of oligonucleotide (ON) medicines from a
historical perspective by listing the landmark discoveries in this field. The various biological …

miRNA therapeutics: a new class of drugs with potential therapeutic applications in the heart

BC Bernardo, JYY Ooi, RCY Lin… - Future medicinal …, 2015 - Taylor & Francis
miRNAs are small non-coding RNAs (ncRNAs), which regulate gene expression. Here, the
authors describe the contribution of miRNAs to cardiac biology and disease. They discuss …

[HTML][HTML] Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose

J Germer, AL Lessl, J Pöhmerer, M Grau… - Journal of Controlled …, 2024 - Elsevier
Double pH-responsive xenopeptide carriers containing succinoyl tetraethylene pentamine
(Stp) and lipo amino fatty acids (LAFs) were evaluated for CRISPR/Cas9 based genome …

Compositions for treating muscular dystrophy

EM Kaye - US Patent 9,506,058, 2016 - Google Patents
2020-01-09 Assigned to BIOPHARMA CREDIT PLC reassignment BIOPHARMA CREDIT
PLC CORRECTIVE ASSIGNMENT TO CORRECT THE TYPOGRAPHICAL ERROR APP. NO …

Antisense oligonucleotides for inducing exon skip** and methods of use thereof

SD Wilton, S Fletcher, G McClorey - US Patent 9,447,415, 2016 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
35781530&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Antisense molecules and methods for treating pathologies

SD Wilton, S Fletcher, A Adams, P Meloni - US Patent 9,228,187, 2016 - Google Patents
2015-08-10 Assigned to THE UNIVERSITY OF WESTERN AUSTRALIA reassignment THE
UNIVERSITY OF WESTERN AUSTRALIA ASSIGNMENT OF ASSIGNORS INTEREST (SEE …

Antisense oligonucleotides for inducing exon skip** and methods of use thereof

SD Wilton, S Fletcher, G McClorey - US Patent 9,175,286, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
35781530&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Antisense oligonucleotides for inducing exon skip** and methods of use thereof

SD Wilton, S Fletcher, G McClorey - US Patent 9,024,007, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
35781530&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Antisense oligonucleotides for inducing exon skip** and methods of use thereof

SD Wilton, S Fletcher, G McClorey - US Patent 9,441,229, 2016 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
35781530&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Antisense oligonucleotides for inducing exon skip** and methods of use thereof

SD Wilton, S Fletcher, G McClorey - US Patent 9,249,416, 2016 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
35781530&utm_source= google_patent&utm_medium= platform_link&utm_campaign …