Abstract Purpose Esophageal pressure (Pes) is a minimally invasive advanced respiratory
monitoring method with the potential to guide management of ventilation support and …

Ventilation is inherently a dynamic process. The present-day clinical practice of
concentrating on the static inflation characteristics of the individual tidal cycle (plateau …

Background: The ventilator works mechanically on the lung parenchyma. The authors set
out to obtain the proof of concept that ventilator-induced lung injury (VILI) depends on the …

Postoperative pulmonary complications are associated with increased morbidity, length of
hospital stay, and mortality after major surgery. Intraoperative lung-protective mechanical …

Deterioration of lung function during the first week of COVID-19 has been observed when
patients remain with insufficient respiratory support. Patient self-inflicted lung injury (P-SILI) …

The adverse effects of mechanical ventilation in acute respiratory distress syndrome (ARDS)
arise from two main causes: unphysiological increases of transpulmonary pressure and …

Rationale: Baseline characteristics and management have changed over time in patients
requiring mechanical ventilation; however, the impact of these changes on patient outcomes …

Several factors have been recognized as possible triggers of ventilator-induced lung injury
(VILI). The first is pressure (thus the 'barotrauma'), then the volume (hence the 'volutrauma') …

Rationale: The use of extracorporeal membrane oxygenation (ECMO) in patients who are
awake and spontaneously breathing may represent a novel bridging strategy toward lung …

Rationale: Pressures and volumes needed to induce ventilator-induced lung injury in
healthy lungs are far greater than those applied in diseased lungs. A possible explanation …