The vestibulospinal nucleus is a locus of balance development

KR Hamling, K Harmon, Y Kimura… - Journal of …, 2024 - Soc Neuroscience
Mature vertebrates maintain posture using vestibulospinal neurons that transform sensed
instability into reflexive commands to spinal motor circuits. Postural stability improves across …

Diving into the zebrafish brain: exploring neuroscience frontiers with genetic tools, imaging techniques, and behavioral insights

O Doszyn, T Dulski, J Zmorzynska - Frontiers in Molecular …, 2024 - frontiersin.org
The zebrafish (Danio rerio) is increasingly used in neuroscience research. Zebrafish are
relatively easy to maintain, and their high fecundity makes them suitable for high-throughput …

Defects in exosome biogenesis are associated with sensorimotor defects in zebrafish vps4a mutants

A Shipman, Y Gao, D Liu, S Sun, J Zang… - Journal of …, 2024 - jneurosci.org
Mutations in human VPS4A are associated with neurodevelopmental defects, including
motor delays and defective muscle tone. VPS4A encodes a AAA-ATPase required for …

Evolutionarily conserved brainstem architecture enables gravity-guided vertical navigation

Y Zhu, H Gelnaw, F Auer, KR Hamling, DE Ehrlich… - PLoS …, 2024 - journals.plos.org
The sensation of gravity anchors our perception of the environment and is important for
navigation. However, the neural circuits that transform gravity into commands for navigation …

Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (Danio rerio)

F Auer, K Nardone, K Matsuda, M Hibi, D Schoppik - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Cerebellar dysfunction leads to postural instability. Recent work in freely moving rodents has
transformed investigations of cerebellar contributions to posture. However, the combined …

Medial and lateral vestibulospinal projections to the cervical spinal cord of the squirrel monkey

R Boyle - Frontiers in Neurology, 2025 - frontiersin.org
Introduction The brainstem vestibular nuclei neurons receive synaptic inputs from inner ear
acceleration-sensing hair cells, cerebellar output neurons, and ascending signals from …

[HTML][HTML] Multisensory strategies for postural compensation after lateral line loss

SN Davis, Y Zhu, D Schoppik - bioRxiv, 2024 - ncbi.nlm.nih.gov
To control elevation underwater, aquatic vertebrates integrate multisensory information (eg,
vestibular, visual, proprioceptive) to guide posture and swim kinematics. Here we …

[HTML][HTML] A brainstem circuit for gravity-guided vertical navigation

Y Zhu, H Gelnaw, F Auer, KR Hamling, DE Ehrlich… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The sensation of gravity anchors our perception of the environment and is crucial for
navigation. However, the neural circuits that transform gravity into commands for navigation …

Sleep pressure modulates single-neuron synapse dynamics in zebrafish

A Suppermpool, DG Lyons, E Broom, J Rihel - bioRxiv, 2023 - biorxiv.org
Sleep is a nearly universal behaviour with unclear functions1. The Synaptic Homeostasis
Hypothesis (SHY) proposes that sleep is required to renormalize the increases in synaptic …