Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …

Mitochondria are highly dynamic organelles undergoing cycles of fusion and fission to
modulate their morphology, distribution, and function, which are referred as 'mitochondrial …

Mitochondria, the membrane-bound cell organelles that supply most of the energy needed
for cell function, are highly regulated, dynamic organelles bearing the ability to alter both …

Doxorubicin (Dox) is a widely used antineoplastic agent that can cause heart failure. Dox
cardiotoxicity is closely associated with mitochondrial damage. Mitochondrial fission and …

Diabetes is accompanied by several complications. Higher prevalence of cancers,
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …

Defective mitochondrial dynamics through aberrant interactions between mitochondria and
actin cytoskeleton is increasingly recognized as a key determinant of cardiac fragility after …

Mitochondria are essential organelles that produce the cellular energy source, ATP.
Dysfunctional mitochondria are involved in the pathophysiology of heart disease, which is …

The past decade has witnessed a number of exciting developments in the field of
mitochondrial dynamics–a phenomenon in which changes in mitochondrial shape and …

Mitochondrial health is critically dependent on the ability of mitochondria to undergo
changes in mitochondrial morphology, a process which is regulated by mitochondrial …

Cardiomyopathy affects approximately 1 in 500 adults and is the leading cause of death.
Familial cases are common, and mutations in many genes are involved in cardiomyopathy …