Role of human macrophage polarization in inflammation during infectious diseases
Experimental models have often been at the origin of immunological paradigms such as the
M1/M2 dichotomy following macrophage polarization. However, this clear dichotomy in …
M1/M2 dichotomy following macrophage polarization. However, this clear dichotomy in …
Dual RNA-seq of pathogen and host
AJ Westermann, SA Gorski, J Vogel - Nature Reviews Microbiology, 2012 - nature.com
A comprehensive understanding of host–pathogen interactions requires a knowledge of the
associated gene expression changes in both the pathogen and the host. Traditional, probe …
associated gene expression changes in both the pathogen and the host. Traditional, probe …
MicroRNAs: biological regulators in pathogen–host interactions
An inflammatory response is essential for combating invading pathogens. Several effector
components, as well as immune cell populations, are involved in mounting an immune …
components, as well as immune cell populations, are involved in mounting an immune …
The pathogenicity and virulence of Leishmania-interplay of virulence factors with host defenses
Leishmaniasis is a group of disease caused by the intracellular protozoan parasite of the
genus Leishmania. Infection by different species of Leishmania results in various host …
genus Leishmania. Infection by different species of Leishmania results in various host …
Transcriptional patterns in both host and bacterium underlie a daily rhythm of anatomical and metabolic change in a beneficial symbiosis
Mechanisms for controlling symbiont populations are critical for maintaining the associations
that exist between a host and its microbial partners. We describe here the transcriptional …
that exist between a host and its microbial partners. We describe here the transcriptional …
Next-generation phage display: integrating and comparing available molecular tools to enable cost-effective high-throughput analysis
Background Combinatorial phage display has been used in the last 20 years in the
identification of protein-ligands and protein-protein interactions, uncovering relevant …
identification of protein-ligands and protein-protein interactions, uncovering relevant …
Transcriptomic profiling of gene expression and RNA processing during Leishmania major differentiation
Protozoan parasites of the genus Leishmania are the etiological agents of leishmaniasis, a
group of diseases with a worldwide incidence of 0.9–1.6 million cases per year. We used …
group of diseases with a worldwide incidence of 0.9–1.6 million cases per year. We used …
Human microRNAs in host–parasite interaction: a review
MicroRNAs (miRNAs) are a group of small noncoding RNA molecules with significant
capacity to regulate the gene expression at the post-transcriptional level in a sequence …
capacity to regulate the gene expression at the post-transcriptional level in a sequence …
MicroRNA Expression Profile in Human Macrophages in Response to Leishmania major Infection
J Lemaire, G Mkannez, FZ Guerfali… - PLoS neglected …, 2013 - journals.plos.org
Background Leishmania (L.) are intracellular protozoan parasites able to survive and
replicate in the hostile phagolysosomal environment of infected macrophages. They cause …
replicate in the hostile phagolysosomal environment of infected macrophages. They cause …
An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani …
Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …