Modern analytical techniques in metabolomics analysis

A Zhang, H Sun, P Wang, Y Han, X Wang - Analyst, 2012 - pubs.rsc.org
Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …

[HTML][HTML] Metabolome changes in cerebral ischemia

TH Shin, DY Lee, S Basith, B Manavalan, MJ Paik… - Cells, 2020 - mdpi.com
Cerebral ischemia is caused by perturbations in blood flow to the brain that trigger
sequential and complex metabolic and cellular pathologies. This leads to brain tissue …

The paradigm change from reactive medical services to 3PM in ischemic stroke: a holistic approach utilising tear fluid multi-omics, mitochondria as a vital biosensor …

O Golubnitschaja, J Polivka Jr, P Potuznik, M Pesta… - EPMA Journal, 2024 - Springer
Worldwide stroke is the second leading cause of death and the third leading cause of death
and disability combined. The estimated global economic burden by stroke is over US $891 …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

[HTML][HTML] Applications of metabolomics in forensic toxicology and forensic medicine

M Szeremeta, K Pietrowska… - International Journal of …, 2021 - mdpi.com
Forensic toxicology and forensic medicine are unique among all other medical fields
because of their essential legal impact, especially in civil and criminal cases. New high …

Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review

AH Emwas, C Luchinat, P Turano, L Tenori, R Roy… - Metabolomics, 2015 - Springer
The metabolic composition of human biofluids can provide important diagnostic and
prognostic information. Among the biofluids most commonly analyzed in metabolomic …

Recent and potential developments of biofluid analyses in metabolomics

A Zhang, H Sun, P Wang, Y Han, X Wang - Journal of proteomics, 2012 - Elsevier
Metabolomics, one of the 'omic'sciences in systems biology, is the global assessment and
validation of endogenous small-molecule metabolites within a biologic system. Analysis of …

Comprehensive metabolomic profiling and incident cardiovascular disease: a systematic review

M Ruiz‐Canela, A Hruby, CB Clish… - Journal of the …, 2017 - ahajournals.org
Background Metabolomics is a promising tool of cardiovascular biomarker discovery. We
systematically reviewed the literature on comprehensive metabolomic profiling in …

[HTML][HTML] Identification and validation of urinary metabolite biomarkers for major depressive disorder

P Zheng, Y Wang, L Chen, D Yang, H Meng… - Molecular & cellular …, 2013 - Elsevier
Major depressive disorder (MDD) is a widespread and debilitating mental disorder.
However, there are no biomarkers available to aid in the diagnosis of this disorder. In this …

[HTML][HTML] Metabolomics: A useful tool for ischemic stroke research

W Li, C Shao, C Li, H Zhou, L Yu, J Yang, H Wan… - Journal of …, 2023 - Elsevier
Ischemic stroke (IS) is a multifactorial and heterogeneous disease. Despite years of studies,
effective strategies for the diagnosis, management and treatment of stroke are still lacking in …