A single-cell transcriptome atlas profiles early organogenesis in human embryos
The early window of human embryogenesis is largely a black box for developmental
biologists. Here we probed the cellular diversity of 4–6 week human embryos when …
biologists. Here we probed the cellular diversity of 4–6 week human embryos when …
Same, same but different: Exploring Plasmodium cell division during liver stage development
M Roques, A Bindschedler, R Beyeler… - PLoS …, 2023 - journals.plos.org
Plasmodium parasites have a complex life cycle alternating between a mosquito and a
vertebrate host. Following the bite of an Anopheles female mosquito, Plasmodium …
vertebrate host. Following the bite of an Anopheles female mosquito, Plasmodium …
Molecular signature of subtypes of non-small-cell lung cancer by large-scale transcriptional profiling: identification of key modules and genes by weighted gene co …
M Niemira, F Collin, A Szalkowska, A Bielska… - Cancers, 2019 - mdpi.com
Non-small-cell lung cancer (NSCLC) represents a heterogeneous group of malignancies
consisting essentially of adenocarcinoma (ADC) and squamous cell carcinoma (SCC) …
consisting essentially of adenocarcinoma (ADC) and squamous cell carcinoma (SCC) …
Single-cell analysis of endometriosis reveals a coordinated transcriptional programme driving immunotolerance and angiogenesis across eutopic and ectopic tissues
Endometriosis is characterized by the growth of endometrial-like tissue outside the uterus. It
affects many women during their reproductive age, causing years of pelvic pain and …
affects many women during their reproductive age, causing years of pelvic pain and …
Immune cell gene signatures for profiling the microenvironment of solid tumors
The immune composition of the tumor microenvironment regulates processes including
angiogenesis, metastasis, and the response to drugs or immunotherapy. To facilitate the …
angiogenesis, metastasis, and the response to drugs or immunotherapy. To facilitate the …
Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte system
The mononuclear phagocyte system (MPS) is a family of cells including progenitors,
circulating blood monocytes, resident tissue macrophages, and dendritic cells (DCs) present …
circulating blood monocytes, resident tissue macrophages, and dendritic cells (DCs) present …
Single-cell chromatin accessibility profiling reveals a self-renewing muscle satellite cell state
A balance between self-renewal and differentiation is critical for the regenerative capacity of
tissue-resident stem cells. In skeletal muscle, successful regeneration requires the …
tissue-resident stem cells. In skeletal muscle, successful regeneration requires the …
Reference transcriptomes of porcine peripheral immune cells created through bulk and single-cell RNA sequencing
Pigs are a valuable human biomedical model and an important protein source supporting
global food security. The transcriptomes of peripheral blood immune cells in pigs were …
global food security. The transcriptomes of peripheral blood immune cells in pigs were …
Genetic analyses of 104 phenotypes in 20,900 Chinese pregnant women reveal pregnancy-specific discoveries
H **ao, L Li, M Yang, X Zhang, J Zhou, J Zeng, Y Zhou… - Cell Genomics, 2024 - cell.com
Monitoring biochemical phenotypes during pregnancy is vital for maternal and fetal health,
allowing early detection and management of pregnancy-related conditions to ensure safety …
allowing early detection and management of pregnancy-related conditions to ensure safety …
Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard
Differentiation of multipotent stem cells into mature cells is fundamental for development and
homeostasis of mammalian tissues, and requires the coordinated induction of lineage …
homeostasis of mammalian tissues, and requires the coordinated induction of lineage …