Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …

The tumor microenvironment is replete with factors secreted and internalized by surrounding
cells. Exosomes are nano-sized, protein-embedded, membrane-bound vesicles that are …

Extracellular vesicles (EVs) are small membranous particles that can mediate cell-to-cell
communication and which are divided into at least three categories according to their …

Over the past three decades, extracellular vesicles (EVs) have arisen as important mediators
of intercellular communication that are involved in the transmission of biological signals …

Simple Summary The distinct molecular and biological properties of exosomes, together
with their abundance and stability, make them an ideal target in liquid biopsies for early …

Regenerative medicine aims to promote the replacement of tissues lost to damage or
disease. While positive outcomes have been observed experimentally, challenges remain in …

Patients with advanced prostate cancer (PCa) frequently develop skeletal metastases that
are associated with fractures, disability, and increased mortality. Within the bone metastatic …

The αVβ6 integrin, an epithelial-specific cell surface receptor absent in normal prostate and
expressed during prostate cancer (PrCa) progression, is a therapeutic target in many …

Extracellular vesicles (EVs) are shed by many different cell types. Their nucleic acids content
offers new opportunities for biomarker research in different solid tumors. The role of EV RNA …

Abstract Characterization of cell surface proteome differences between cancer and healthy
cells is a valuable approach for the identification of novel diagnostic and therapeutic targets …