Mechanisms of drug-induced tolerance in Mycobacterium tuberculosis

SN Goossens, SL Sampson… - Clinical microbiology …, 2020 - Am Soc Microbiol
Successful treatment of tuberculosis (TB) can be hampered by Mycobacterium tuberculosis
populations that are temporarily able to survive antibiotic pressure in the absence of drug …

Antitumor effects of carvacrol and thymol: a systematic review

LA Sampaio, LTS Pina, MR Serafini… - Frontiers in …, 2021 - frontiersin.org
Background: It is estimated that one in five people worldwide faces a diagnosis of a
malignant neoplasm during their lifetime. Carvacrol and its isomer, thymol, are natural …

Carvone and its pharmacological activities: A systematic review

LTS Pina, MR Serafini, MA Oliveira, LA Sampaio… - Phytochemistry, 2022 - Elsevier
Natural products from plants have gained prominence in the search for therapeutic
alternatives. Monoterpenes, such as carvone, are suggested as candidates for the treatment …

Amino acid–derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development

A Parthasarathy, EJ Borrego, MA Savka… - Journal of Biological …, 2021 - ASBMB
For millennia, humanity has relied on plants for its medicines, and modern pharmacology
continues to reexamine and mine plant metabolites for novel compounds and to guide …

Antitumor effect of melatonin on breast cancer in experimental models: A systematic review

PIR Franco, JR do Carmo Neto, AC Milhomem… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Breast cancer is the most frequent malignant neoplasm in females. While conventional
treatments such as chemotherapy and radiotherapy are available, they are highly invasive …

RNA-sequencing analyses of small bacterial RNAs and their emergence as virulence factors in host-pathogen interactions

I Diallo, P Provost - International journal of molecular sciences, 2020 - mdpi.com
Proteins have long been considered to be the most prominent factors regulating so-called
invasive genes involved in host-pathogen interactions. The possible role of small non …

Medicinal activities of Tualang honey: a systematic review

ANSS Azman, JJ Tan, MNH Abdullah, H Bahari… - … Medicine and Therapies, 2024 - Springer
Natural products derived from various sources, including plants, have garnered significant
interest as alternative therapeutic options. Among these, Tualang honey, extracted from the …

Identifying assessment criteria for in vitro studies: a method and item bank

P Whaley, RB Blain, D Draper, AA Rooney… - Toxicological …, 2024 - academic.oup.com
To support the development of appraisal tools for assessing the quality of in vitro studies, we
developed a method for literature-based discovery of study assessment criteria, used the …

Insights into non-coding RNAs as novel antimicrobial drugs

G Parmeciano Di Noto, MC Molina, C Quiroga - Frontiers in genetics, 2019 - frontiersin.org
Multidrug resistant bacteria are a serious worldwide problem, especially carbapenem-
resistant Enterobacteriaceae (such as Klebsiella pneumoniae and Escherichia coli) …

Drug resistance and gene transfer mechanisms in respiratory/oral bacteria

S Jiang, J Zeng, X Zhou, Y Li - Journal of Dental Research, 2018 - journals.sagepub.com
Growing evidence suggests the existence of new antibiotic resistance mechanisms. Recent
studies have revealed that quorum-quenching enzymes, such as MacQ, are involved in both …