Glycogen synthase kinase‐3β: A multifaceted player in ischemia‐reperfusion injury and its therapeutic prospects

J Li, Y Zhang, R Tang, H Liu, X Li, W Lei… - Journal of Cellular …, 2024 - Wiley Online Library
Ischemia‐reperfusion injury (IRI) results in irreversible metabolic dysfunction and structural
damage to tissues or organs, posing a formidable challenge in the field of organ …

[HTML][HTML] Brain Glycogen—Its Metabolic Role in Neuronal Health and Neurological Disorders—An Extensive Narrative Review

AI Beltran-Velasco - Metabolites, 2025 - mdpi.com
Background: Brain glycogen is imperative for neuronal health, as it supports energy
demands and metabolic processes. This review examines the pathways involved in …

The Current Potential Pathogenesis of Amyotrophic Lateral Sclerosis

S Jiang, R Xu - Molecular Neurobiology, 2024 - Springer
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease mainly
characterized by the accumulation of ubiquitinated proteins in the affected motor neurons. At …

Axonal transcriptome reveals upregulation of PLK1 as a protective mechanism in response to increased DNA damage in FUSP525L spinal motor neurons

V Zimyanin, BP Dash, D Grossmann, T Simolka… - bioRxiv, 2024 - biorxiv.org
Mutations in the gene FUSED IN SARCOMA (FUS) are among the most frequently occurring
genetic forms of amyotrophic lateral sclerosis (ALS). Early pathogenesis of FUS-ALS …