Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

The discovery of cuproptosis, a copper-dependent mechanism of programmed cell death,
has provided a way for cancer treatment. However, cuproptosis has inherent limitations …

Molecular imaging via afterglow luminescence minimizes tissue autofluorescence and
increases the signal-to-noise ratio. However, the induction of afterglow requires the prior …

Cancer immunotherapies, such as immune checkpoint blockade and chimeric antigen
receptor (CAR) T cell therapy, have transformed clinical oncology. However, limited patient …

Precise and efficient image-guided immunotherapy holds great promise for cancer
treatment. Here, we report a self-accelerated nanoplatform combining an aggregation …

Programmed death-ligand 1 (PD-L1) is a specialized shield on tumor cells that evades the
immune system. Even inhibited by PD-L1 antibodies, a cycling process constantly transports …

Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Glioblastoma (GBM) is an aggressive brain cancer with an immunosuppressive tumor
microenvironment. Here, a copper-based nanoplatform BSO-CAT@ MOF-199@ DDM …

Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …