Terahertz (THz= 10 12 Hz) radiation has attracted wide attention for its unprecedented
sensing ability and its noninvasive and nonionizing properties. Tremendous strides in THz …

The structure and function of biomolecules are strongly influenced by their hydration shells.
Structural fluctuations and molecular excitations of hydrating water molecules cover a broad …

[**] We thank Dr. Vladislav Litosh for carrying out preliminary work. Support from the National
Institutes of Health, National Institute of General Medical Sciences (GM 28384), the National …

Water is essential for life in many ways, and without it biomolecules might no longer truly be
biomolecules. In particular, water is important to the structure, stability, dynamics, and …

We present an overview of recent static and time-resolved vibrational spectroscopic studies
of liquid water from ambient conditions to the supercooled state, as well as of crystalline and …

This review deals with dynamics of water molecules in the hydration layer that surrounds
selfassemblies and proteins in aqueous solutions. This topic has not only seen a vigorous …

Almost all biological macromoleculessproteins (enzymes) and DNAsare inactive in the
absence of water. Hydration of a protein/enzyme is particularly important for the stability of …

The terahertz region lies between the microwave and infrared regions of the electromagnetic
spectrum such that it is strongly attenuated by water and very sensitive to water content …

A proximity effect has been invoked to explain the enhanced activity of enzyme cascades on
DNA scaffolds. Using the cascade reaction carried out by glucose oxidase and horseradish …

Protein motions are essential for function. Comparing protein processes with the dielectric
fluctuations of the surrounding solvent shows that they fall into two classes: nonslaved and …