The sodium/iodide symporter (NIS): molecular physiology and preclinical and clinical applications

S Ravera, A Reyna-Neyra, G Ferrandino… - Annual review of …, 2017 - annualreviews.org
Active iodide (I−) transport in both the thyroid and some extrathyroidal tissues is mediated by
the Na+/I− symporter (NIS). In the thyroid, NIS-mediated I− uptake plays a pivotal role in …

[PDF][PDF] RETRACTED: The Oncolytic Virus in Cancer Diagnosis and Treatment

G Cao, X He, Q Sun, S Chen, K Wan, X Xu… - Frontiers in …, 2020 - frontiersin.org
Cancer has always been an enormous threat to human health and survival. Surgery,
radiotherapy, and chemotherapy could improve the survival of cancer patients, but most …

Oncolytic virotherapy for cancer: clinical experience

S Chaurasiya, Y Fong, SG Warner - Biomedicines, 2021 - mdpi.com
Oncolytic viruses are a new class of therapeutics which are largely in the experimental
stage, with just one virus approved by the FDA thus far. While the concept of oncolytic …

The sodium iodide symporter (NIS): novel applications for radionuclide imaging and treatment

C Spitzweg, PJ Nelson, E Wagner… - Endocrine-related …, 2021 - erc.bioscientifica.com
Cloning of the sodium iodide symporter (NIS) 25 years ago has opened an exciting chapter
in molecular thyroidology with the characterization of NIS as one of the most powerful …

Oncolytic viruses for triple negative breast cancer and beyond

S **, Q Wang, H Wu, D Pang, S Xu - Biomarker Research, 2021 - Springer
Biological therapy is considered an alternative treatment capable of eliciting the same
effects on tumors as surgery, radiotherapy, and chemotherapy. As a major player in …

Oncolytic poxviruses

WM Chan, G McFadden - Annual review of virology, 2014 - annualreviews.org
Current standard treatments of cancer can prolong survival of many cancer patients but
usually do not effectively cure the disease. Oncolytic virotherapy is an emerging therapeutic …

A novel vaccinia virus with dual oncolytic and anti-angiogenic therapeutic effects against triple-negative breast cancer

S Gholami, A Marano, NG Chen, RJ Aguilar… - Breast cancer research …, 2014 - Springer
Vascular endothelial growth factor (VEGF) expression is higher in triple-negative breast
cancers (TNBC) compared to other subtypes and is reported to predict incidence of distant …

The use of the NIS reporter gene for optimizing oncolytic virotherapy

A Miller, SJ Russell - Expert opinion on biological therapy, 2016 - Taylor & Francis
Introduction: Oncolytic viruses are experimental cancer therapies being translated to the
clinic. They are unique in their ability to amplify within the body, therefore requiring careful …

Viruses as nanomedicine for cancer

N Badrinath, J Heo, SY Yoo - International Journal of …, 2016 - Taylor & Francis
Oncolytic virotherapy, a type of nanomedicine in which oncolytic viruses (OVs) are used to
selectively infect and lyse cancer cells, is an emerging field in cancer therapy. Some OVs …

[HTML][HTML] Oncolytic viruses: A novel treatment strategy for breast cancer

M Javanbakht, S Tahmasebzadeh, L Cegolon… - Genes & …, 2023 - Elsevier
Breast cancer, an unceasingly occurring neoplasm, is one of the major determinants of
mortality in women. Several ineffective attempts have been pursued using with conventional …