Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights

J Masschelein, M Jenner, GL Challis - Natural product reports, 2017 - pubs.rsc.org
Covering: up to 2017 The overwhelming majority of antibiotics in clinical use originate from
Gram-positive Actinobacteria. In recent years, however, Gram-negative bacteria have …

Bioactive compounds: a goldmine for defining new strategies against pathogenic bacterial biofilms?

A Pompilio, M Scocchi, ML Mangoni… - Critical reviews in …, 2023 - Taylor & Francis
Most human infectious diseases are caused by microorganisms growing as biofilms. These
three-dimensional self-organized communities are embedded in a dense matrix allowing …

Cyclic dipeptides: Biological activities and self‐assembled materials

K Zhao, R **ng, X Yan - Peptide Science, 2021 - Wiley Online Library
Cyclic dipeptides (CDPs) are the smallest cyclic peptides containing 2, 5‐diketopiperazine
rings. CDPs have advantages of structures and properties, including excellent hydrogen …

High levels of oxidative stress create a microenvironment that significantly decreases the diversity of the microbiota in diabetic chronic wounds and promotes biofilm …

JH Kim, PR Ruegger, EG Lebig… - Frontiers in Cellular …, 2020 - frontiersin.org
Diabetics chronic wounds are characterized by high levels of oxidative stress (OS) and are
often colonized by biofilm-forming bacteria that severely compromise healing and can result …

Injectable thermogel incorporating reactive oxygen species scavenger and nitric oxide donor to accelerate the healing process of diabetic wounds

THT Do, TKT Pham, PT Ha, TP Nguyen, TP Dao… - International Journal of …, 2023 - Elsevier
The healing of diabetic wounds is challenging due to redox imbalances. Herein, the
thermogelling system AR-ACP hydrogel, with encapsulated biosafe nitric oxide (NO) donor L …

Modulation of Intestinal Microbiota in Solea senegalensis Fed Low Dietary Level of Ulva ohnoi

ST Tapia-Paniagua, M Fumanal, V Anguís… - Frontiers in …, 2019 - frontiersin.org
Gastrointestinal (GI) microbiota has a relevant role in animal nutrition, modulation of the
immune system and protection against pathogen invasion. Interest in algae as source of …

Antimicrobial activity of cyclic dipeptides produced by Lactobacillus plantarum LBP-K10 against multidrug-resistant bacteria, pathogenic fungi, and influenza A virus

MK Kwak, R Liu, SO Kang - Food Control, 2018 - Elsevier
The antimicrobial activity of lactic acid bacteria (LAB) is well recognized, particularly
because they can produce antimicrobial cyclic dipeptides (CDPs). CDPs serve as attractive …

Carvacrol acts on the larval midgut of Spodoptera frugiperda by destroying the tissue structure and altering the bacterial community

J Zhang, C Liu, X **e, X Yu, Y Huang, R Tang… - Journal of Asia-Pacific …, 2024 - Elsevier
The fall armyworm, Spodoptera frugiperda, has become a global invasive pest in recent
years, threatening agricultural production. Carvacrol (CAR) is a multifunctional plant-derived …

[HTML][HTML] Complementary activities of host defence peptides and antibiotics in combating antimicrobial resistant bacteria

PR Lennard, PS Hiemstra, PH Nibbering - Antibiotics, 2023 - mdpi.com
Due to their ability to eliminate antimicrobial resistant (AMR) bacteria and to modulate the
immune response, host defence peptides (HDPs) hold great promise for the clinical …

Anti-Klebsiella pneumoniae activity of secondary metabolism of Achromobacter from the intestine of Periplaneta americana

Y Ma, P Guo, X Chen, M Xu, W Liu, X ** - BMC microbiology, 2023 - Springer
Background Klebsiella pneumoniae is one of the main pathogens of clinical isolation and
nosocomial infections, as K. pneumoniae show broad-spectrum resistance to β-lactam and …