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Recent advances on cell culture platforms for in vitro drug screening and cell therapies: from conventional to microfluidic strategies
BD Cardoso, EMS Castanheira… - Advanced …, 2023 - Wiley Online Library
The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical
research based on biologically accurate screening approaches. Since establishing the 2D in …
research based on biologically accurate screening approaches. Since establishing the 2D in …
Design of pressure-driven microfluidic networks using electric circuit analogy
This article reviews the application of electric circuit methods for the analysis of pressure-
driven microfluidic networks with an emphasis on concentration-and flow-dependent …
driven microfluidic networks with an emphasis on concentration-and flow-dependent …
The origins and the future of microfluidics
GM Whitesides - nature, 2006 - nature.com
The manipulation of fluids in channels with dimensions of tens of micrometres—microfluidics—
has emerged as a distinct new field. Microfluidics has the potential to influence subject areas …
has emerged as a distinct new field. Microfluidics has the potential to influence subject areas …
Cells on chips
Microsystems create new opportunities for the spatial and temporal control of cell growth
and stimuli by combining surfaces that mimic complex biochemistries and geometries of the …
and stimuli by combining surfaces that mimic complex biochemistries and geometries of the …
Concentration gradient generation methods based on microfluidic systems
X Wang, Z Liu, Y Pang - RSC advances, 2017 - pubs.rsc.org
Various concentration gradient generation methods based on microfluidic systems are
summarized in this paper. The review covers typical structural characteristics, gradient …
summarized in this paper. The review covers typical structural characteristics, gradient …
Micro total analysis systems. Latest advancements and trends
The area of micro total analysis systems (μTAS), also called “lab on a chip”, miniaturized or
microfluidic analysis systems, is a rapidly develo** field. During the last several years, we …
microfluidic analysis systems, is a rapidly develo** field. During the last several years, we …
Biomolecular gradients in cell culture systems
TM Keenan, A Folch - Lab on a Chip, 2008 - pubs.rsc.org
Biomolecule gradients have been shown to play roles in a wide range of biological
processes including development, inflammation, wound healing, and cancer metastasis …
processes including development, inflammation, wound healing, and cancer metastasis …
Review on cell mechanics: experimental and modeling approaches
The interplay between the mechanical properties of cells and the forces that they produce
internally or that are externally applied to them play an important role in maintaining the …
internally or that are externally applied to them play an important role in maintaining the …
Biological applications of microfluidic gradient devices
Molecular gradients play an important role in diverse physiological and pathological
phenomena such as immune response, wound healing, development and cancer …
phenomena such as immune response, wound healing, development and cancer …
Design, fabrication and characterization of drug delivery systems based on lab-on-a-chip technology
Lab-on-a-chip technology is an emerging field evolving from the recent advances of micro-
and nanotechnologies. The technology allows the integration of various components into a …
and nanotechnologies. The technology allows the integration of various components into a …