The pathogenesis of keratoconus

AE Davidson, S Hayes, AJ Hardcastle, SJ Tuft - Eye, 2014 - nature.com
Keratoconus (KC) is a common degenerative condition that frequently results in visual loss
with an onset typically in early adulthood. It is the single most common reason for …

Natural organic and inorganic–hydroxyapatite biopolymer composite for biomedical applications

S Sathiyavimal, S Vasantharaj, F LewisOscar… - Progress in Organic …, 2020 - Elsevier
Regenerative medicine is becoming a fast-growing technique in today's scenario for
biomedical advancement. Researchers around the globe has suggested the involvement of …

Bioprintable, cell-laden silk fibroin–gelatin hydrogel supporting multilineage differentiation of stem cells for fabrication of three-dimensional tissue constructs

S Das, F Pati, YJ Choi, G Rijal, JH Shim, SW Kim… - Acta biomaterialia, 2015 - Elsevier
Bioprinting has exciting prospects for printing three-dimensional (3-D) tissue constructs by
delivering living cells with appropriate matrix materials. However, progress in this field is …

United States multicenter clinical trial of corneal collagen crosslinking for keratoconus treatment

PS Hersh, RD Stulting, D Muller, DS Durrie, RK Rajpal… - Ophthalmology, 2017 - Elsevier
Purpose To evaluate the safety and efficacy of corneal collagen crosslinking (CXL) for the
treatment of progressive keratoconus. Design Prospective, randomized, multicenter …

A review of structural and biomechanical changes in the cornea in aging, disease, and photochemical crosslinking

BJ Blackburn, MW Jenkins, AM Rollins… - … in bioengineering and …, 2019 - frontiersin.org
The study of corneal biomechanics is motivated by the tight relationship between
biomechanical properties and visual function within the ocular system. For instance …

Development of graphitic carbon nitride quantum dots-based oxygen self-sufficient platforms for enhanced corneal crosslinking

M Yang, T Chen, X Chen, H Pan, G Zhao… - Nature …, 2024 - nature.com
Keratoconus, a disorder characterized by corneal thinning and weakening, results in vision
loss. Corneal crosslinking (CXL) can halt the progression of keratoconus. The development …

Corneal collagen crosslinking: a systematic review

N Sorkin, D Varssano - Ophthalmologica, 2014 - karger.com
Keratoconus (KCN) is an ectatic disorder with progressive corneal thinning and a clinical
picture of corneal protrusion, progressive irregular astigmatism, corneal fibrosis and visual …

Collagen cross-linking using rose bengal and green light to increase corneal stiffness

D Cherfan, EE Verter, S Melki, TE Gisel… - … & visual science, 2013 - iovs.arvojournals.org
Purpose.: Photochemical cross-linking of corneal collagen is an evolving treatment for
keratoconus and other ectatic disorders. We evaluated collagen cross-linking by rose …

Current perspectives on corneal collagen crosslinking (CXL)

SK Subasinghe, KC Ogbuehi, GJ Dias - Graefe's Archive for Clinical and …, 2018 - Springer
Corneal collagen crosslinking has revolutionized the treatment of keratoconus and post-
refractive corneal ectasia in the past decade. Corneal crosslinking with riboflavin and …

Corneal cross‐linking–a review

KM Meek, S Hayes - Ophthalmic and Physiological Optics, 2013 - Wiley Online Library
Purpose To review cross‐linking the cornea using riboflavin and ultraviolet A light, which
has been widely adopted, refined and applied in a range of corneal surgeries and …