A test in context: lipoprotein (a) diagnosis, prognosis, controversies, and emerging therapies

S Tsimikas - Journal of the American College of Cardiology, 2017 - jacc.org
Evidence that elevated lipoprotein (a)(Lp [a]) levels contribute to cardiovascular disease
(CVD) and calcific aortic valve stenosis (CAVS) is substantial. Development of isoform …

Structure, function, and genetics of lipoprotein (a)

K Schmidt, A Noureen, F Kronenberg… - Journal of lipid …, 2016 - ASBMB
Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …

Oxidized phospholipids, lipoprotein (a), and progression of calcific aortic valve stenosis

R Capoulade, KL Chan, C Yeang, P Mathieu… - Journal of the American …, 2015 - jacc.org
Abstract Background: Elevated lipoprotein (a)(Lp [a]) is associated with aortic stenosis (AS).
Oxidized phospholipids (OxPL) are key mediators of calcification in valvular cells and are …

Oxidized phospholipids as a unifying theory for lipoprotein (a) and cardiovascular disease

MB Boffa, ML Koschinsky - Nature Reviews Cardiology, 2019 - nature.com
Epidemiological and clinical studies over the past decade have firmly established that
elevated plasma concentrations of lipoprotein (a)(Lp (a)) are an important, independent and …

Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases

A Trpkovic, I Resanovic, J Stanimirovic… - Critical reviews in …, 2015 - Taylor & Francis
Atherosclerosis is a life-long illness that begins with risk factors, which in turn contribute to
the development of subclinical disease, followed by the establishment of overt …

[HTML][HTML] Lipoprotein (a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality

Emerging Risk Factors Collaboration - JAMA: the journal of the …, 2009 - ncbi.nlm.nih.gov
Lipoprotein(a) Concentration and the Risk of Coronary Heart Disease, Stroke, and Nonvascular
Mortality - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Lipoprotein (a): resurrected by genetics

F Kronenberg, G Utermann - Journal of internal medicine, 2013 - Wiley Online Library
Plasma lipoprotein (a)[L p (a)] is a quantitative genetic trait with a very broad and skewed
distribution, which is largely controlled by genetic variants at the LPA locus on chromosome …

Lipid-related markers and cardiovascular disease prediction

R Used - Jama, 2012 - jamanetwork.com
Context The value of assessing various emerging lipid-related markers for prediction of first
cardiovascular events is debated. Objective To determine whether adding information on …

Generation and biological activities of oxidized phospholipids

VN Bochkov, OV Oskolkova, KG Birukov… - Antioxidants & redox …, 2010 - liebertpub.com
Glycerophospholipids represent a common class of lipids critically important for integrity of
cellular membranes. Oxidation of esterified unsaturated fatty acids dramatically changes …

The role of oxidized low‐density lipoproteins in atherosclerosis: the myths and the facts

G Maiolino, G Rossitto, P Caielli… - Mediators of …, 2013 - Wiley Online Library
The oxidative modification hypothesis of atherosclerosis, which assigns to oxidized low‐
density lipoproteins (LDLs) a crucial role in atherosclerosis initiation and progression, is still …