Medial and orbital frontal cortex in decision-making and flexible behavior

MC Klein-Flügge, A Bongioanni, MFS Rushworth - Neuron, 2022 - cell.com
The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

A tripartite view of the posterior cingulate cortex

BL Foster, SR Koslov, L Aponik-Gremillion… - Nature Reviews …, 2023 - nature.com
The posterior cingulate cortex (PCC) is one of the least understood regions of the cerebral
cortex. By contrast, the anterior cingulate cortex has been the subject of intensive …

The macaque anterior cingulate cortex translates counterfactual choice value into actual behavioral change

EF Fouragnan, BKH Chau, D Folloni, N Kolling… - Nature …, 2019 - nature.com
The neural mechanisms mediating sensory-guided decision-making have received
considerable attention, but animals often pursue behaviors for which there is currently no …

Control of movement vigor and decision making during foraging

T Yoon, RB Geary, AA Ahmed… - Proceedings of the …, 2018 - National Acad Sciences
During foraging, animals decide how long to stay at a patch and harvest reward, and then,
they move with certain vigor to another location. How does the brain decide when to leave …

[HTML][HTML] Could Alzheimer's disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?

RJ Johnson, DR Tolan, D Bredesen, M Nagel… - The American Journal of …, 2023 - Elsevier
An important aspect of survival is to assure enough food, water, and oxygen. Here, we
describe a recently discovered response that favors survival in times of scarcity, and it is …

The posterior cingulate cortex: Insights from structure and function

R Leech, J Smallwood - Handbook of clinical neurology, 2019 - Elsevier
The posterior cingulate cortex (PCC)(Brodmann areas 23/31) is one of the least well-
understood regions of the cortex. The PCC has very high levels of metabolic consumption …

General mechanisms of task engagement in the primate frontal cortex

J Grohn, N Khalighinejad, CI Jahn… - Nature …, 2024 - nature.com
Staying engaged is necessary to maintain goal-directed behaviors. Despite this,
engagement exhibits continuous, intrinsic fluctuations. Even in experimental settings …

Prospection, perseverance, and insight in sequential behavior

N Kolling, J Scholl, A Chekroud, HA Trier… - Neuron, 2018 - cell.com
Real-world decisions have benefits occurring only later and dependent on additional
decisions taken in the interim. We investigated this in a novel decision-making task in …

Foraging as an evidence accumulation process

JD Davidson, A El Hady - PLoS computational biology, 2019 - journals.plos.org
The patch-leaving problem is a canonical foraging task, in which a forager must decide to
leave a current resource in search for another. Theoretical work has derived optimal …

Neural evidence of switch processes during semantic and phonetic foraging in human memory

NB Lundin, JW Brown, BT Johns… - Proceedings of the …, 2023 - National Acad Sciences
Humans may retrieve words from memory by exploring and exploiting in “semantic space”
similar to how nonhuman animals forage for resources in physical space. This has been …