Pathophysiology of type 2 diabetes mellitus

U Galicia-Garcia, A Benito-Vicente, S Jebari… - International journal of …, 2020 - mdpi.com
Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused
by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and …

Coronary heart disease risk: low-density lipoprotein and beyond

GE Shaya, TM Leucker, SR Jones, SS Martin… - Trends in cardiovascular …, 2022 - Elsevier
Coronary heart disease (CHD) is the leading cause of morbidity and mortality world-wide
and has been characterized as a chronic immunoinflammatory, fibroproliferative disease …

High-density lipoproteins, reverse cholesterol transport and atherogenesis

HJ Pownall, C Rosales, BK Gillard… - Nature Reviews …, 2021 - nature.com
Plasma HDL-cholesterol concentrations correlate negatively with the risk of atherosclerotic
cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its …

Effects of aerobic exercise on lipids and lipoproteins

Y Wang, D Xu - Lipids in health and disease, 2017 - Springer
Dyslipidemia is the risk of cardiovascular disease, and their relationship is clear. Lowering
serum cholesterol can reduce the risk of coronary heart disease. At present, the main …

Soy and health update: evaluation of the clinical and epidemiologic literature

M Messina - Nutrients, 2016 - mdpi.com
Soyfoods have long been recognized as sources of high-quality protein and healthful fat, but
over the past 25 years these foods have been rigorously investigated for their role in chronic …

[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis

MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Cholesterol and lipoprotein metabolism and atherosclerosis: recent advances in reverse cholesterol transport

HH Wang, G Garruti, M Liu, P Portincasa… - Annals of …, 2018 - medigraphic.com
Atherosclerosis is characterized by lipid accumulation, inflammatory response, cell death
and fibrosis in the arterial wall, and is a major pathological basis for ischemic coronary heart …

Obesity-related changes in high-density lipoprotein metabolism and function

JT Stadler, G Marsche - International journal of molecular sciences, 2020 - mdpi.com
In obese individuals, atherogenic dyslipidemia is a very common and important factor in the
increased risk of cardiovascular disease. Adiposity-associated dyslipidemia is characterized …

HDL and cardiovascular disease

DJ Rader, GK Hovingh - The Lancet, 2014 - thelancet.com
The cholesterol contained within HDL is inversely associated with risk of coronary heart
disease and is a key component of predicting cardiovascular risk. However, despite its …

High-density lipoprotein cholesterol and cause-specific mortality in individuals without previous cardiovascular conditions: the CANHEART study

DT Ko, DA Alter, H Guo, M Koh, G Lau… - Journal of the American …, 2016 - jacc.org
Background: The prognostic importance of high-density lipoprotein cholesterol (HDL-C) as a
specific risk factor for cardiovascular (CV) disease has been challenged by recent clinical …