Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations

H Zhu, D Bi, Y Zhang, C Kong, J Du, X Wu… - Signal transduction and …, 2022 - nature.com
The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet
regimen that mimics the metabolism of the fasting state to induce the production of ketone …

Tumor glycolysis, an essential sweet tooth of tumor cells

S Paul, S Ghosh, S Kumar - Seminars in cancer biology, 2022 - Elsevier
Cancer cells undergo metabolic alterations to meet the immense demand for energy,
building blocks, and redox potential. Tumors show glucose-avid and lactate-secreting …

Develo** dietary interventions as therapy for cancer

SR Taylor, JN Falcone, LC Cantley… - Nature Reviews …, 2022 - nature.com
Cancer cells acquire distinct metabolic preferences based on their tissue of origin, genetic
alterations and degree of interaction with systemic hormones and metabolites. These …

[HTML][HTML] Ketogenic diet in the treatment of cancer–where do we stand?

DD Weber, S Aminzadeh-Gohari, J Tulipan… - Molecular …, 2020 - Elsevier
Background Cancer is one of the greatest public health challenges worldwide, and we still
lack complementary approaches to significantly enhance the efficacy of standard anticancer …

Metabolism of pancreatic cancer: paving the way to better anticancer strategies

C Qin, G Yang, J Yang, B Ren, H Wang, G Chen… - Molecular cancer, 2020 - Springer
Pancreatic cancer is currently one of the most lethal diseases. In recent years, increasing
evidence has shown that reprogrammed metabolism may play a critical role in the …

Remodelling of the translatome controls diet and its impact on tumorigenesis

H Yang, VA Zingaro, J Lincoff, H Tom, S Oikawa… - Nature, 2024 - nature.com
Fasting is associated with a range of health benefits,,,,–. How fasting signals elicit changes
in the proteome to establish metabolic programmes remains poorly understood. Here we …

Ketogenic diet in cancer prevention and therapy: molecular targets and therapeutic opportunities

WH Talib, AI Mahmod, A Kamal, HM Rashid… - Current issues in …, 2021 - mdpi.com
Although cancer is still one of the most significant global challenges facing public health, the
world still lacks complementary approaches that would significantly enhance the efficacy of …

[HTML][HTML] Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth

L Yang, T TeSlaa, S Ng, M Nofal, L Wang, T Lan… - Med, 2022 - cell.com
Background Ketogenic diet is a potential means of augmenting cancer therapy. Here, we
explore ketone body metabolism and its interplay with chemotherapy in pancreatic cancer …

Dietary interventions and precision nutrition in cancer therapy

C Martínez-Garay, N Djouder - Trends in Molecular Medicine, 2023 - cell.com
In recent years dietary interventions have become a promising tool in cancer treatment and
have demonstrated a powerful ability to alter metabolism and tumor growth, development …

Feasibility, safety, and beneficial effects of MCT-based ketogenic diet for breast cancer treatment: a randomized controlled trial study

A Khodabakhshi, ME Akbari, HR Mirzaei… - Nutrition and …, 2020 - Taylor & Francis
The present study was aimed to evaluate the safety, tolerability, and beneficial effects of a
ketogenic diet (KD) on body composition and blood parameters and survival in patients with …