Advancing chemical carcinogenicity prediction modeling: opportunities and challenges

A Mittal, G Ahuja - Trends in Pharmacological Sciences, 2023 - cell.com
Carcinogenicity assessment of any compound is a laborious and expensive exercise with
several associated ethical and practical concerns. While artificial intelligence (AI) offers …

OdoriFy: a conglomerate of artificial intelligence–driven prediction engines for olfactory decoding

R Gupta, A Mittal, V Agrawal, S Gupta, K Gupta… - Journal of Biological …, 2021 - jbc.org
The molecular mechanisms of olfaction, or the sense of smell, are relatively underexplored
compared with other sensory systems, primarily because of its underlying molecular …

Artificial intelligence uncovers carcinogenic human metabolites

A Mittal, SK Mohanty, V Gautam, S Arora… - Nature Chemical …, 2022 - nature.com
The genome of a eukaryotic cell is often vulnerable to both intrinsic and extrinsic threats
owing to its constant exposure to a myriad of heterogeneous compounds. Despite the …

Gcoupler: An AI-enhanced tool unveiled Endogenous Intracellular Allosteric Modulators of Evolutionary Conserved GPCR-Gα Interface

SK Mohanty, A Mittal, A Gaur, Namra, S Duari… - bioRxiv, 2023 - biorxiv.org
Traditionally, the exogenous allosteric modulators of G protein-coupled receptors (GPCRs)
have been extensively investigated due to their pharmacological significance. However, to …

Artificial Intelligence Uncovers Evolutionarily Conserved Intracellular Allosteric Modulators of GPCR-Gα Interface

S Mohanty, A Mittal, A Gaur, S Solanki, S Kumar… - 2023 - researchsquare.com
Traditionally, the exogenous allosteric modulators of G protein-coupled receptors (GPCRs)
have been extensively investigated due to their pharmacological significance. However, to …