Actin dynamics, architecture, and mechanics in cell motility

L Blanchoin, R Boujemaa-Paterski… - Physiological …, 2014 - journals.physiology.org
Tight coupling between biochemical and mechanical properties of the actin cytoskeleton
drives a large range of cellular processes including polarity establishment, morphogenesis …

Mechanics of biological networks: from the cell cytoskeleton to connective tissue

RH Pritchard, YYS Huang, EM Terentjev - Soft matter, 2014 - pubs.rsc.org
From the cell cytoskeleton to connective tissues, fibrous networks are ubiquitous in
metazoan life as the key promoters of mechanical strength, support and integrity. In recent …

Noncontact three-dimensional map** of intracellular hydromechanical properties by Brillouin microscopy

G Scarcelli, WJ Polacheck, HT Nia, K Patel… - Nature …, 2015 - nature.com
Current measurements of the biomechanical properties of cells require physical contact with
cells or lack subcellular resolution. Here we developed a label-free microscopy technique …

Force feedback controls motor activity and mechanical properties of self-assembling branched actin networks

P Bieling, J Weichsel, R McGorty, P Jreij, B Huang… - Cell, 2016 - cell.com
Branched actin networks—created by the Arp2/3 complex, cap** protein, and a nucleation
promoting factor—generate and transmit forces required for many cellular processes, but …

Branched aramid nanofibers

J Zhu, M Yang, A Emre, JH Bahng, L Xu… - Angewandte Chemie …, 2017 - Wiley Online Library
Interconnectivity of components in three‐dimensional networks (3DNs) is essential for stress
transfer in hydrogels, aerogels, and composites. Entanglement of nanoscale components in …

Biomimetic strain-stiffening in fully synthetic dynamic-covalent hydrogel networks

RC Ollier, Y **ang, AM Yacovelli, MJ Webber - Chemical Science, 2023 - pubs.rsc.org
Mechanoresponsiveness is a ubiquitous feature of soft materials in nature; biological tissues
exhibit both strain-stiffening and self-healing in order to prevent and repair deformation …

Physically based principles of cell adhesion mechanosensitivity in tissues

B Ladoux, A Nicolas - Reports on Progress in Physics, 2012 - iopscience.iop.org
The minimal structural unit that defines living organisms is a single cell. By proliferating and
mechanically interacting with each other, cells can build complex organization such as …

Strain-Stiffening Mechanoresponse in Dynamic-Covalent Cellulose Hydrogels

RC Ollier, MJ Webber - Biomacromolecules, 2024 - ACS Publications
Mechanical stimuli such as strain, force, and pressure are pervasive within and beyond the
human body. Mechanoresponsive hydrogels have been engineered to undergo changes in …

Recycling of the actin monomer pool limits the lifetime of network turnover

A Colin, T Kotila, C Guérin, M Orhant‐Prioux… - The EMBO …, 2023 - embopress.org
Intracellular organization is largely mediated by actin turnover. Cellular actin networks
continuously assemble and disassemble, while maintaining their overall appearance. This …

Actin-network architecture regulates microtubule dynamics

A Colin, P Singaravelu, M Théry, L Blanchoin… - Current Biology, 2018 - cell.com
Coordination between actin filaments and microtubules is critical to complete important
steps during cell division. For instance, cytoplasmic actin filament dynamics play an active …