Wound healing: a cellular perspective
Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …
spatial and temporal synchronization of a variety of cell types with distinct roles in the …
Cancer stem cells revisited
The cancer stem cell (CSC) concept was proposed four decades ago, and states that tumor
growth, analogous to the renewal of healthy tissues, is fueled by small numbers of dedicated …
growth, analogous to the renewal of healthy tissues, is fueled by small numbers of dedicated …
Cancer cell plasticity during tumor progression, metastasis and response to therapy
A Pérez-González, K Bévant, C Blanpain - Nature cancer, 2023 - nature.com
Cell plasticity represents the ability of cells to be reprogrammed and to change their fate and
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …
[HTML][HTML] Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis
Y Feng, M Spezia, S Huang, C Yuan, Z Zeng, L Zhang… - Genes & diseases, 2018 - Elsevier
As the most commonly occurring cancer in women worldwide, breast cancer poses a
formidable public health challenge on a global scale. Breast cancer consists of a group of …
formidable public health challenge on a global scale. Breast cancer consists of a group of …
Linking EMT programmes to normal and neoplastic epithelial stem cells
AW Lambert, RA Weinberg - Nature Reviews Cancer, 2021 - nature.com
Epithelial stem cells serve critical physiological functions in the generation, maintenance
and repair of diverse tissues through their ability to self-renew and spawn more specialized …
and repair of diverse tissues through their ability to self-renew and spawn more specialized …
Tumour heterogeneity and cancer cell plasticity
CE Meacham, SJ Morrison - Nature, 2013 - nature.com
Phenotypic and functional heterogeneity arise among cancer cells within the same tumour
as a consequence of genetic change, environmental differences and reversible changes in …
as a consequence of genetic change, environmental differences and reversible changes in …
Innovative treatment strategies to accelerate wound healing: trajectory and recent advancements
Wound healing is highly specialized dynamic multiple phase process for the repair of
damaged/injured tissues through an intricate mechanism. Any failure in the normal wound …
damaged/injured tissues through an intricate mechanism. Any failure in the normal wound …
Epithelialization in wound healing: a comprehensive review
Significance: Keratinocytes, a major cellular component of the epidermis, are responsible for
restoring the epidermis after injury through a process termed epithelialization. This review …
restoring the epidermis after injury through a process termed epithelialization. This review …
Regeneration of the entire human epidermis using transgenic stem cells
Junctional epidermolysis bullosa (JEB) is a severe and often lethal genetic disease caused
by mutations in genes encoding the basement membrane component laminin-332 …
by mutations in genes encoding the basement membrane component laminin-332 …
Advanced drug delivery systems and artificial skin grafts for skin wound healing
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …
painstakingly long-term treatment with an immense financial burden to healthcare systems …