MicroRNAs: from mechanism to organism

PJ Dexheimer, L Cochella - Frontiers in cell and developmental …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are short, regulatory RNAs that act as post-transcriptional repressors
of gene expression in diverse biological contexts. The emergence of small RNA-mediated …

Convergent and divergent evolution of microRNA‐mediated regulation in metazoans

Y Wang, X Tang, J Lu - Biological Reviews, 2024 - Wiley Online Library
The evolution of microRNAs (miRNAs) has been studied extensively to understand their
roles in gene regulation and evolutionary processes. This review focuses on how miRNA …

Mitochondrial miRNA as epigenomic signatures: visualizing aging-associated heart diseases through a new lens

JS Bhatti, N Khullar, R Vijayvergiya, U Navik… - Ageing Research …, 2023 - Elsevier
Aging bears many hard knocks, but heart disorders earn a particular allusion, being the most
widespread. Cardiovascular diseases (CVDs) are becoming the biggest concern to mankind …

Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis

H Kitai, N Kato, K Ogami, S Komatsu, Y Watanabe… - BMC biology, 2022 - Springer
Background Combinatorial gene regulation by multiple microRNAs (miRNAs) is widespread
and closely spaced target sites often act cooperatively to achieve stronger repression …

Evolutionary dynamics of microRNA target sites across vertebrate evolution

A Simkin, R Geissler, ABR McIntyre, A Grimson - PLoS genetics, 2020 - journals.plos.org
MicroRNAs (miRNAs) control the abundance of the majority of the vertebrate transcriptome.
The recognition sequences, or target sites, for bilaterian miRNAs are found predominantly in …

Cross-kingdom regulation of plant-derived mirnas in modulating insect development

X Chi, Z Wang, Y Wang, Z Liu, H Wang… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs), a class of non-coding small RNAs, are crucial regulatory factors in
plants and animals at the post-transcriptional level. These tiny molecules suppress gene …

Chromosome-scale genome assembly reveals how repeat elements shape non-coding RNA landscapes active during newt limb regeneration

T Brown, K Mishra, A Elewa, S Iarovenko… - Cell Genomics, 2025 - cell.com
Newts have large genomes harboring many repeat elements. How these elements shape
the genome and relate to newts' unique regeneration ability remains unknown. We present …

microRNA-430b targets scavenger receptor class B member 1 (scarb1) and inhibits coloration and carotenoid synthesis in koi carp (Cyprinus carpio L.)

X Tian, N Peng, X Ma, L Wu, X Shi, H Liu, H Song… - Aquaculture, 2022 - Elsevier
In teleost fishes, miR-430 has several paralogs and is widely required for mesoderm
formation and gonad development. However, the functions of miR-430 in skin pigmentation …

Diploid and triploid Chinook salmon (Oncorhynchus tshawytscha) have altered microRNA responses in immune tissues after infection with Vibrio anguillarum

IG Cadonic, JW Heath, B Dixon, PM Craig - Comparative Biochemistry and …, 2023 - Elsevier
Production of sterile fishes through artificial retention of a third set of chromosomes (triploidy)
is a sustainable alternative for aquaculture since it reduces escapee pressure on wild …

Characterization of microRNAs in the cyst nematode Heterodera glycines identifies possible candidates involved in cross-kingdom interactions with its host Glycine …

DT Ste-Croix, RR Bélanger, B Mimee - RNA biology, 2023 - Taylor & Francis
The soybean cyst nematode (SCN–Heterodera glycines) is one of the most damaging pests
to the cultivated soybean worldwide. Using a wide array of stylet-secreted effector proteins …