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Mechanistic modeling of SARS‐CoV‐2 and other infectious diseases and the effects of therapeutics
Modern viral kinetic modeling and its application to therapeutics is a field that attracted the
attention of the medical, pharmaceutical, and modeling communities during the early days of …
attention of the medical, pharmaceutical, and modeling communities during the early days of …
Mathematical analysis of viral replication dynamics and antiviral treatment strategies: from basic models to age-based multi-scale modeling
Viral infectious diseases are a global health concern, as is evident by recent outbreaks of
the middle east respiratory syndrome, Ebola virus disease, and re-emerging zika, dengue …
the middle east respiratory syndrome, Ebola virus disease, and re-emerging zika, dengue …
[BUKU][B] An introduction to mathematical epidemiology
M Martcheva - 2015 - Springer
This book is an introductory text to the methods and tools that are nowadays widely used
and accepted in the mathematical epidemiology literature. It is intended to start from a …
and accepted in the mathematical epidemiology literature. It is intended to start from a …
[HTML][HTML] Mathematical analysis and simulation of a stochastic COVID-19 Lévy jump model with isolation strategy
This paper investigates the dynamics of a COVID-19 stochastic model with isolation strategy.
The white noise as well as the Lévy jump perturbations are incorporated in all compartments …
The white noise as well as the Lévy jump perturbations are incorporated in all compartments …
Global dynamics of a delayed within-host viral infection model with both virus-to-cell and cell-to-cell transmissions
Y Yang, L Zou, S Ruan - Mathematical biosciences, 2015 - Elsevier
A within-host viral infection model with both virus-to-cell and cell-to-cell transmissions and
three distributed delays is investigated, in which the first distributed delay describes the …
three distributed delays is investigated, in which the first distributed delay describes the …
Computer-aided drug design: the next 20 years
JH Van Drie - Journal of computer-aided molecular design, 2007 - Springer
This perspectives article has been taken from a talk the author gave at the symposium in
honor of Yvonne C. Martin's retirement, held at the American Chemical Society spring …
honor of Yvonne C. Martin's retirement, held at the American Chemical Society spring …
How robust are estimates of key parameters in standard viral dynamic models?
Mathematical models of viral infection have been developed, fitted to data, and provide
insight into disease pathogenesis for multiple agents that cause chronic infection, including …
insight into disease pathogenesis for multiple agents that cause chronic infection, including …
Viral kinetic modeling: state of the art
Viral kinetic (VK) modeling has led to increased understanding of the within host dynamics
of viral infections and the effects of therapy. Here we review recent developments in the …
of viral infections and the effects of therapy. Here we review recent developments in the …
A comprehensive hepatitis C viral kinetic model explaining cure
E Snoeck, P Chanu, M Lavielle… - Clinical …, 2010 - Wiley Online Library
We propose a model that characterizes and links the complexity and diversity of clinically
observed hepatitis C viral kinetics to sustained virologic response (SVR)—the primary …
observed hepatitis C viral kinetics to sustained virologic response (SVR)—the primary …
Modelling hepatitis C therapy—predicting effects of treatment
Mathematically modelling changes in HCV RNA levels measured in patients who receive
antiviral therapy has yielded many insights into the pathogenesis and effects of treatment on …
antiviral therapy has yielded many insights into the pathogenesis and effects of treatment on …