Idiopathic pulmonary fibrosis (IPF) affects hundreds of thousands of people worldwide,
reducing their quality of life and leading to death from respiratory failure within years of …

The role of inflammation in idiopathic pulmonary fibrosis (IPF) is controversial. If
inflammation were critical to the disease process, lung pathology would demonstrate an …

Background Mediastinal lymph node enlargement is prevalent in patients with idiopathic
pulmonary fibrosis (IPF). Studies investigating whether this phenomenon reflects specific …

Inducing memory CD8+ T cells specific for conserved antigens from influenza A virus (IAV) is
a potential strategy for broadly protective vaccines. Here we show that memory CD8+ T cells …

Idiopathic pulmonary fibrosis (IPF) is a devastating disease of unknown etiology, for which
there is no curative pharmacological therapy. Bleomycin, an anti-neoplastic agent that …

Although the pathogenesis of pulmonary fibrosis remains unclear, it is known to involve
epithelial injury and epithelial-mesenchymal transformation (EMT) as a consequence of …

Every breath we take contains potentially harmful pathogens or allergens. Dendritic cells
(DCs), monocytes, and macrophages are essential in maintaining a delicate balance of …

Abstract Objective Primary Sjogren's syndrome (pSS) is a heterogeneous chronic
autoimmune disorder characterized by lymphocyte infiltration of the exocrine glands and the …

Idiopathic pulmonary fibrosis (IPF) affects an increasing number of people globally, yet
treatment options remain limited. At present, conventional treatments depending on drug …

Recently, patients with tobacco smoke induced emphysema have been shown to exhibit
classical signs of T cell mediated autoimmunity characterized by autoantibody production …