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Human genome variability, natural selection and infectious diseases
Highlights•Demographic history and natural selection shaped human genome
diversity.•Infections represented a major environmental selective pressure for human …
diversity.•Infections represented a major environmental selective pressure for human …
[HTML][HTML] Recent advances in the study of fine-scale population structure in humans
Empowered by modern genoty** and large samples, population structure can be
accurately described and quantified even when it only explains a fraction of a percent of total …
accurately described and quantified even when it only explains a fraction of a percent of total …
Detecting genomic signatures of natural selection with principal component analysis: application to the 1000 genomes data
To characterize natural selection, various analytical methods for detecting candidate
genomic regions have been developed. We propose to perform genome-wide scans of …
genomic regions have been developed. We propose to perform genome-wide scans of …
Assessing the effect of sequencing depth and sample size in population genetics inferences
M Fumagalli - PloS one, 2013 - journals.plos.org
Next-Generation Sequencing (NGS) technologies have dramatically revolutionised research
in many fields of genetics. The ability to sequence many individuals from one or multiple …
in many fields of genetics. The ability to sequence many individuals from one or multiple …
Space is the place: effects of continuous spatial structure on analysis of population genetic data
Real geography is continuous, but standard models in population genetics are based on
discrete, well-mixed populations. As a result, many methods of analyzing genetic data …
discrete, well-mixed populations. As a result, many methods of analyzing genetic data …
On the genes, genealogies, and geographies of Quebec
Population genetic models only provide coarse representations of real-world ancestry. We
used a pedigree compiled from 4 million parish records and genotype data from 2276 …
used a pedigree compiled from 4 million parish records and genotype data from 2276 …
Do dental nonmetric traits actually work as proxies for neutral genomic data? Some answers from continental‐and global‐level analyses
Objectives Crown and root traits, like those in the Arizona State University Dental
Anthropology System (ASUDAS), are seemingly useful as genetic proxies. However, recent …
Anthropology System (ASUDAS), are seemingly useful as genetic proxies. However, recent …
[HTML][HTML] Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of …
Genome sequencing of the 5,300-year-old mummy of the Tyrolean Iceman, found in 1991
on a glacier near the border of Italy and Austria, has yielded new insights into his origin and …
on a glacier near the border of Italy and Austria, has yielded new insights into his origin and …
Clines without classes: how to make sense of human variation
This article examines Shiao, Bode, Beyer, and Selvig's (2012) arguments in their article “The
Genomic Challenge to the Social Construction of Race” and finds that their claims are based …
Genomic Challenge to the Social Construction of Race” and finds that their claims are based …
Species delimitation and mitonuclear discordance within a species complex of biting midges
The inability to distinguish between species can be a serious problem in groups responsible
for pathogen transmission. Culicoides biting midges transmit many pathogenic agents …
for pathogen transmission. Culicoides biting midges transmit many pathogenic agents …