Expression and function of the cholinergic system in immune cells

T Fujii, M Mashimo, Y Moriwaki, H Misawa… - Frontiers in …, 2017 - frontiersin.org
T and B cells express most cholinergic system components—eg, acetylcholine (ACh),
choline acetyltransferase (ChAT), acetylcholinesterase, and both muscarinic and nicotinic …

Neuronal and extraneuronal nicotinic acetylcholine receptors

M Zoli, S Pucci, A Vilella, C Gotti - Current neuropharmacology, 2018 - ingentaconnect.com
Neuronal nicotinic acetylcholine receptors (nAChRs) belong to a super-family of Cysloop
ligand-gated ion channels that respond to endogenous acetylcholine (ACh) or other …

Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection

J Egea, I Buendia, E Parada, E Navarro, R Leon… - Biochemical …, 2015 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) are widely distributed throughout the central
nervous system, being expressed in neurons and non-neuronal cells, where they participate …

International Union of Pharmacology. LXX. Subtypes of γ-aminobutyric acidA receptors: classification on the basis of subunit composition, pharmacology, and function …

RW Olsen, W Sieghart - Pharmacological reviews, 2008 - Elsevier
In this review we attempt to summarize experimental evidence on the existence of defined
native GABA A receptor subtypes and to produce a list of receptors that actually seem to …

Acetylcholine beyond neurons: the non‐neuronal cholinergic system in humans

I Wessler, CJ Kirkpatrick - British journal of pharmacology, 2008 - Wiley Online Library
Animal life is controlled by neurons and in this setting cholinergic neurons play an important
role. Cholinergic neurons release ACh, which via nicotinic and muscarinic receptors (n‐and …

Diversity of native nicotinic receptor subtypes in mammalian brain

M Zoli, F Pistillo, C Gotti - Neuropharmacology, 2015 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a heterogeneous family of
pentameric ligand-gated cation channels that are expressed throughout the brain and …

[HTML][HTML] Physiological functions of the cholinergic system in immune cells

T Fujii, M Mashimo, Y Moriwaki, H Misawa… - Journal of …, 2017 - Elsevier
T and B cells, macrophages and dendritic cells (DCs) all express most of the components
necessary for a functional cholinergic system. This includes choline acetyltransferase …

Nicotine-like effects of the neonicotinoid insecticides acetamiprid and imidacloprid on cerebellar neurons from neonatal rats

J Kimura-Kuroda, Y Komuta, Y Kuroda, M Hayashi… - PloS one, 2012 - journals.plos.org
Background Acetamiprid (ACE) and imidacloprid (IMI) belong to a new, widely used class of
pesticide, the neonicotinoids. With similar chemical structures to nicotine, neonicotinoids …

Diversity of vertebrate nicotinic acetylcholine receptors

NS Millar, C Gotti - Neuropharmacology, 2009 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) are pentameric neurotransmitter receptors. They
are members of the Cys-loop family of ligand-gated ion channels which also include …

Evolutionary game design

C Browne, F Maire - … on Computational Intelligence and AI in …, 2010 - ieeexplore.ieee.org
It is easy to create new combinatorial games but more difficult to predict those that will
interest human players. We examine the concept of game quality, its automated …