Selection and behavior of CD4+ CD25+ T cells in vivo: lessons from T cell receptor transgenic models

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CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells

MA Schneider, JG Meingassner, M Lipp… - The Journal of …, 2007 - rupress.org
CCR7-mediated migration of naive T cells into the secondary lymphoid organs is a
prerequisite for their encounter with mature dendritic cells, the productive presentation of …
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Current developments with peptide-based human tumor vaccines

K Khazaie, A Bonertz, P Beckhove - Current opinion in oncology, 2009 - journals.lww.com
Current developments with peptide-based human tumor vaccines : Current Opinion in
Oncology Current developments with peptide-based human tumor vaccines : Current Opinion …
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Prevention of allograft rejection by amplification of Foxp3+ CD4+ CD25+ regulatory T cells

G **a, M Shah, X Luo - Translational Research, 2009 - Elsevier
CD4+ CD25+ T cells were identified originally as potent suppressors of autoimmunity and
were later termed “natural regulatory T cells” or nTreg cells. Subsequently, a transcription …
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The control of CD4+CD25+Foxp3+regulatory T cell survival

P Pandiyan, MJ Lenardo - Biology direct, 2008 - Springer
Abstract CD4+ CD25+ Foxp3+ regulatory T (T reg) cells are believed to play an important
role in suppressing autoimmunity and maintaining peripheral tolerance. How their survival is …
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Notch3 and pTα/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells

AF Campese, P Grazioli, S Colantoni… - International …, 2009 - academic.oup.com
Dysregulated generation and/or function of naturally occurring 'CD4+ CD25+ regulatory T
cells'(Tregs) play key role in the development of autoimmune diseases, including type 1 …
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Regulatory T cells: how do they find their space in the immunological arena?

D D'Ambrosio - Seminars in cancer biology, 2006 - Elsevier
After more of a decade of controversy, the concept of suppressor T cells initially promoted by
Gershon, has now become an established paradigm. Current knowledge withholds that …
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A novel model on DST-induced transplantation tolerance by the transfer of self-specific donor tTregs to a haplotype-matched organ recipient

AM Mohr Gregoriussen, HG Bohr - Frontiers in immunology, 2017 - frontiersin.org
Donor-specific blood transfusion (DST) can lead to significant prolongation of allograft
survival in experimental animal models and sometimes human recipients of solid organs …
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Regulatory T cells essential to prevent the loss of self-tolerance in murine models of erythrocyte-specific autoantibody responses

CE Calkins - Immunologic research, 2011 - Springer
The spontaneous appearance of anti-erythrocyte autoantibodies resulting in autoimmune
hemolytic anemia described in NZB mice more than 40 years ago provided a model for the …
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Visualizing The Dynamics Of Immune Surveillance In Brain Tumors By Intravital Multiphoton Microscopy

F Nwajei - 2017 - digitalcommons.library.tmc.edu
Multiple physiological mechanisms exist to protect the brain from immunemediated neuronal
damage 150. However, these same protective mechanisms make it challenging to tease …
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The role of MHC-II dependent events in the suppression mediated by CD4+ Foxp3+ regulatory T cells

FD Mmanywa - 2008 - search.proquest.com
Abstract CD4+ Foxp3+ regulatory T cells (Tregs) and antigen presenting cells (APCs) play
an important role in maintaining peripheral tolerance but are otherwise exploited by tumors …
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