Evaluation and management of penicillin allergy: a review

ES Shenoy, E Macy, T Rowe, KG Blumenthal - Jama, 2019 - jamanetwork.com
Importance β-Lactam antibiotics are among the safest and most effective antibiotics. Many
patients report allergies to these drugs that limit their use, resulting in the use of broad …

Influence of the gut microbiome, diet, and environment on risk of colorectal cancer

M Song, AT Chan, J Sun - Gastroenterology, 2020 - Elsevier
Researchers have discovered associations between elements of the intestinal microbiome
(including specific microbes, signaling pathways, and microbiota-related metabolites) and …

Global antibiotic consumption and usage in humans, 2000–18: a spatial modelling study

AJ Browne, MG Chipeta… - The Lancet Planetary …, 2021 - thelancet.com
Background Antimicrobial resistance (AMR) is a serious threat to global public health. WHO
emphasises the need for countries to monitor antibiotic consumption to combat AMR. Many …

Trends in US Burden of Clostridioides difficile Infection and Outcomes

AY Guh, Y Mu, LG Winston, H Johnston… - … England Journal of …, 2020 - Mass Medical Soc
Abstract Background Efforts to prevent Clostridioides difficile infection continue to expand
across the health care spectrum in the United States. Whether these efforts are reducing the …

[HTML][HTML] Rapid identification of pathogenic bacteria using Raman spectroscopy and deep learning

CS Ho, N Jean, CA Hogan, L Blackmon… - Nature …, 2019 - nature.com
Raman optical spectroscopy promises label-free bacterial detection, identification, and
antibiotic susceptibility testing in a single step. However, achieving clinically relevant speeds …

National estimates of healthcare costs associated with multidrug-resistant bacterial infections among hospitalized patients in the United States

RE Nelson, KM Hatfield, H Wolford… - Clinical Infectious …, 2021 - academic.oup.com
Background Treating patients with infections due to multidrug-resistant pathogens often
requires substantial healthcare resources. The purpose of this study was to report estimates …

Antimicrobial resistance, mechanisms and its clinical significance

MA Abushaheen, AJ Fatani, M Alosaimi, W Mansy… - Disease-a-Month, 2020 - Elsevier
Antimicrobial agents play a key role in controlling and curing infectious disease. Soon after
the discovery of the first antibiotic, the challenge of antibiotic resistance commenced …

[HTML][HTML] Focus: drug development: Penicillin's discovery and antibiotic resistance: lessons for the future?

M Lobanovska, G Pilla - The Yale journal of biology and medicine, 2017 - ncbi.nlm.nih.gov
Undoubtedly, the discovery of penicillin is one of the greatest milestones in modern
medicine. 2016 marks the 75th anniversary of the first systemic administration of penicillin in …

[HTML][HTML] Core elements of outpatient antibiotic stewardship

GV Sanchez - MMWR. Recommendations and Reports, 2016 - cdc.gov
Summary The Core Elements of Outpatient Antibiotic Stewardship provides a framework for
antibiotic stewardship for outpatient clinicians and facilities that routinely provide antibiotic …

Global trends in antibiotic consumption during 2016–2023 and future projections through 2030

EY Klein, I Impalli, S Poleon, P Denoel… - Proceedings of the …, 2024 - pnas.org
Antibiotic resistance is a global public health threat. Many factors contribute to this issue,
with human antibiotic consumption being significant among them. Analyzing trends and …