In the 19 th century, the discovery of general anesthesia revolutionized medical care. In the
21 st century, anesthetics have become indispensable tools to study consciousness. Here, I …

Remarkable advancements have been made in understanding the pathogenesis of
Alzheimer's disease, Parkinson's disease, and other neurological disease; in our depth of …

Abstract Background Disorders of consciousness (DoC) are frequently encountered in both,
acute and chronic brain injuries. In many countries, early withdrawal of life-sustaining …

Patient narratives from two investigational deep brain stimulation trials for traumatic brain
injury and obsessive‐compulsive disorder reveal that injury and illness rob individuals of …

The thalamus has a key role in mediating cortical–subcortical interactions but is often
neglected in neuroimaging studies, which mostly focus on changes in cortical structure and …

Nervous system diseases are among the most common diseases globally, posing a severe
threat to patients' quality of life and placing a considerable burden on families and society …

Background Following acute and sub-acute rehabilitation from severe traumatic brain injury
(TBI), minimal to no efficacious interventions to treat ongoing cognitive deficits are available …

Recovery of consciousness after coma remains one of the most challenging areas for
accurate diagnosis and effective therapeutic engagement in the clinical neurosciences …

Background Self-injurious behaviours (SIB) are repetitive, non-accidental movements that
result in physical damage inflicted upon oneself, without suicidal intent. SIB are prevalent …

Among the existing research on the treatment of disorders of consciousness (DOC), deep
brain stimulation (DBS) offers a highly promising therapeutic approach. This comprehensive …