[HTML][HTML] Pharmacological basis and new insights of taxifolin: A comprehensive review

A Das, R Baidya, T Chakraborty, AK Samanta… - Biomedicine & …, 2021 - Elsevier
The pharmacological characteristics of phytochemicals have prompted a lot of interest in
their application in disease management. Due to the high incidence of cancer related …

Nanotechnology strategies to advance outcomes in clinical cancer care

CM Hartshorn, MS Bradbury, GM Lanza, AE Nel… - ACS …, 2018 - ACS Publications
Ongoing research into the application of nanotechnology for cancer treatment and diagnosis
has demonstrated its advantages within contemporary oncology as well as its intrinsic …

Targeting EMT in cancer: opportunities for pharmacological intervention

FM Davis, TA Stewart, EW Thompson… - Trends in …, 2014 - cell.com
The spread of cancer cells to distant organs represents a major clinical challenge in the
treatment of cancer. Epithelial–mesenchymal transition (EMT) has emerged as a key …

Melatonin: an inhibitor of breast cancer

SM Hill, VP Belancio, RT Dauchy… - Endocrine-related …, 2015 - erc.bioscientifica.com
The present review discusses recent work on melatonin-mediated circadian regulation, the
metabolic and molecular signaling mechanisms that are involved in human breast cancer …

Cancer stem cells and epithelial-to-mesenchymal transition (EMT)-phenotypic cells: are they cousins or twins?

D Kong, Y Li, Z Wang, FH Sarkar - Cancers, 2011 - mdpi.com
Cancer stem cells (CSCs) are cells within a tumor that possess the capacity to self-renew
and maintain tumor-initiating capacity through differentiation into the heterogeneous …

Epithelial–mesenchymal transition and breast cancer: Role, molecular mechanisms and clinical impact

C Foroni, M Broggini, D Generali, G Damia - Cancer treatment reviews, 2012 - Elsevier
Epithelial–mesenchymal transition (EMT) is defined by the loss of epithelial characteristics
and the acquisition of a mesenchymal phenotype. In this process, cells acquire molecular …

Epithelial Mesenchymal Transition Traits in Human Breast Cancer Cell Lines Parallel the CD44hi/CD24lo/- Stem Cell Phenotype in Human Breast Cancer

T Blick, H Hugo, E Widodo, M Waltham, C Pinto… - Journal of mammary …, 2010 - Springer
We review here the recently emerging relationship between epithelial-mesenchymal
transition (EMT) and breast cancer stem cells (BCSC), and provide analyses of published …

Inhibition of dipeptidyl peptidase-4 accelerates epithelial–mesenchymal transition and breast cancer metastasis via the CXCL12/CXCR4/mTOR axis

F Yang, Y Takagaki, Y Yoshitomi, T Ikeda, J Li… - Cancer research, 2019 - AACR
Abstract Dipeptidyl peptidase (DPP)-4 is a multifunctional glycoprotein involved in various
biological and pathologic processes. DPP-4 has been widely recognized as a therapeutic …

Linkage between obesity leptin and breast cancer

MF Atoum, F Alzoughool… - Breast Cancer: Basic …, 2020 - journals.sagepub.com
Many cancers might be influenced by obesity, including breast cancer, the leading cause of
cancer death among women. Obesity is a complex state associated with multiple …

EMT in developmental morphogenesis

Y Nakaya, G Sheng - Cancer letters, 2013 - Elsevier
Carcinomas, cancers of epithelial origin, constitute the majority of all cancers. Loss of
epithelial characteristics is an early step in carcinoma progression. Malignant transformation …