Glycogen storage diseases (GSDs) are a group of rare, monogenic disorders that share a
defect in the synthesis or breakdown of glycogen. This Primer describes the multi-organ …

The red blood cell depends solely on the anaerobic conversion of glucose by the Embden-
Meyerhof pathway for the generation and storage of high-energy phosphates, which is …

Itaconate has been recently recognized as an anti-inflammatory metabolite involved in the
pathogen–macrophage interface. Due to its weak electrophilicity, itaconate could modify …

Nitric oxide (NO) is a key redox-active, small molecule involved in various aspects of plant
growth and development. Here, we report the identification of an NO accumulation mutant …

The aldolase family members involved in metabolism and glycolysis are present in three
isoforms: ALDOA, ALDOB, and ALDOC. Aldolases are differentially expressed in human …

Pancreatic cancer is an aggressive and devastating disease that is characterized by
uncontrolled progression, invasiveness and resistance to conventional treatment. In the past …

Rhabdomyolysis (RM) is a clinical emergency characterized by fulminant skeletal muscle
damage and release of intracellular muscle components into the blood stream leading to …

Fructose-bisphosphate aldolase A (ALDOA) is a key enzyme in glycolysis and is responsible
for catalyzing the reversible conversion of fructose-1, 6-bisphosphate to glyceraldehydes-3 …

Muscular dystrophies are a group of diseases characterised by the primary wasting of
skeletal muscle, which compromises patient mobility and in the most severe cases originate …

Regarded as the most invasive subtype, triple-negative breast cancer (TNBC) lacks the
expression of estrogen receptors (ERs), progesterone receptors (PRs), and human …