Understanding bacterial biofilms: From definition to treatment strategies

A Zhao, J Sun, Y Liu - Frontiers in cellular and infection microbiology, 2023 - frontiersin.org
Bacterial biofilms are complex microbial communities encased in extracellular polymeric
substances. Their formation is a multi-step process. Biofilms are a significant problem in …

Biofilm therapy for chronic wounds

Y Liu, S Long, H Wang, Y Wang - International wound journal, 2024 - Wiley Online Library
Chronic wounds have been a major factor of serious harm to global public health. At
present, it is known that almost all chronic wounds contain biofilms, which seriously hinder …

Isolation and characterization of a lytic bacteriophage against Pseudomonas aeruginosa

S Sharma, S Datta, S Chatterjee, M Dutta, J Samanta… - Scientific Reports, 2021 - nature.com
In recent years, the use of bacteriophages (or'phages') against multidrug-resistant (MDR)
bacteria including Pseudomonas aeruginosa has drawn considerable attention, globally. In …

[HTML][HTML] Bacteriophage as a potential therapy to control antibiotic-resistant Pseudomonas aeruginosa infection through topical application onto a full-thickness wound …

N Rezk, AS Abdelsattar, D Elzoghby, MM Agwa… - Journal of Genetic …, 2022 - Elsevier
Abstract Background Antibiotic-resistant Pseudomonas aeruginosa (P. aeruginosa) is one of
the most critical pathogens in wound infections, causing high mortality and morbidity in …

Genomic characterization of lytic bacteriophages targeting genetically diverse Pseudomonas aeruginosa clinical isolates

HR Nordstrom, DR Evans, AG Finney, KJ Westbrook… - Iscience, 2022 - cell.com
Pseudomonas aeruginosa infections can be difficult to treat and new therapeutics are
needed. Bacteriophage therapy is a promising alternative to traditional antibiotics, but large …

RETRACTED: Isolation and Characterization of a Novel Lytic Phage, vB_PseuP-SA22, and Its Efficacy against Carbapenem-Resistant Pseudomonas aeruginosa

AD Teklemariam, RR Al-Hindi, MG Alharbi, I Alotibi… - Antibiotics, 2023 - mdpi.com
Carbapenem-resistant Pseudomonas aeruginosa (CRPA) poses a serious public health
threat in multiple clinical settings. In this study, we detail the isolation of a lytic …

Assessment of Phage-Mediated Inhibition and Removal of Multidrug-Resistant Pseudomonas aeruginosa Biofilm on Medical Implants

S Amankwah, M Adisu, K Gorems… - Infection and Drug …, 2022 - Taylor & Francis
Purpose Despite the growing interest in bacteriophage (phage) usage for the prevention,
control, and removal of bacterial biofilms, few scientific data exist on phage applications on …

A novel lytic phage exhibiting a remarkable in vivo therapeutic potential and higher antibiofilm activity against Pseudomonas aeruginosa

A Abdelghafar, A El-Ganiny, G Shaker… - European Journal of …, 2023 - Springer
Background Pseudomonas aeruginosa is a nosocomial bacterium responsible for variety of
infections. Inappropriate use of antibiotics could lead to emergence of multidrug-resistant …

Isolation and Characterization of Lytic Pseudomonas aeruginosa Bacteriophages Isolated from Sewage Samples from Tunisia

I Akremi, M Merabishvili, M Jlidi, A Haj Brahim… - Viruses, 2022 - mdpi.com
Bacteriophages could be a useful adjunct to antibiotics for the treatment of multidrug-
resistant Pseudomonas aeruginosa infections. In this study, lytic P. aeruginosa myoviruses …

Engineered superinfective Pf phage prevents dissemination of Pseudomonas aeruginosa in a mouse burn model

FI Prokopczuk, H Im, J Campos-Gomez, CJ Orihuela… - Mbio, 2023 - Am Soc Microbiol
Pf is a filamentous bacteriophage integrated in the chromosome of most clinical isolates of
Pseudomonas aeruginosa. Under stress conditions, mutations occurring in the Pf genome …