Recent evidence clearly shows that cells respond to various physical cues in their
environments, guiding many cellular processes and tissue morphogenesis, pathology, and …

The geometry of porous scaffolds that are used for bone tissue engineering and/or bone
substitution has recently been shown to significantly influence the cellular response and the …

Tissue scaffolds provide structural support while facilitating tissue growth, but are
challenging to design due to diverse property trade-offs. Here, a computational approach …

Abstract 2D cell culture and preclinical animal models have traditionally been implemented
for investigating the underlying cellular mechanisms of human disease progression …

Although bone is regenerative, its regeneration capacity is limited. For bone defects beyond
a critical size, further intervention is required. As an attractive strategy, bone tissue …

A current medical challenge is the replacement of tissue which can be thought of in terms of
bone tissue engineering approaches. The key problem in bone tissue engineering lies in …

A compatible artificial bone implant requires large pores for enhanced nutrients transports,
small pores to allow cell seeding and bone-like mechanical properties to avoid stress …

In this study, multi‐scale triply periodic minimal surface (TPMS) porous scaffolds with
uniform and radial gradient distribution on pore size were printed based on the selective …

Techniques of bone reconstructive surgery are largely based on conventional, non-cell-
based therapies that rely on the use of durable materials from outside the patient's body. In …

Although a promising progress has been recently accomplished in polymer science, cell
biology, immunology and biotechnology, the biocompatibility of biomaterials still remains a …