Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …

Integrins are vital surface adhesion receptors that mediate interactions between the
extracellular matrix (ECM) and cells and are essential for cell migration and the …

Spheroids and organoids are important novel players in medical and life science research.
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …

Pseudouridine is the most frequent epitranscriptomic modification. However, its cellular
functions remain largely unknown. Here, we show that pseudouridine synthase 7 (PUS7) is …

Brain tumors, although rare, contribute to distinct mortality and morbidity at all ages.
Although there are few therapeutic options for brain tumors, enhanced biological …

Rationale: In the glioblastoma (GBM) microenvironment, tumor-associated macrophages
(TAMs) are prominent components and facilitate tumor growth. The exact molecular …

Glioblastoma (GBM) are the most common tumors of the central nervous system and among
the deadliest cancers in adults. GBM overall survival has not improved over the last decade …

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative
agent of coronavirus disease 2019 (COVID-19), which was rapidly declared a pandemic by …

Despite recent advances in cancer therapeutics, glioblastoma (GBM) remains one of the
most difficult cancers to treat in both the primary and recurrent settings. GBM presents a …

Integrins are the adhesion molecules and transmembrane receptors that consist of α and β
subunits. After binding to extracellular matrix components, integrins trigger intracellular …