Intrinsically disordered proteins (IDPs) are unable to adopt a unique 3D structure under
physiological conditions and thus exist as highly dynamic conformational ensembles. IDPs …

Viruses rely on the reprogramming of cellular processes to enable efficient viral replication;
this often requires subcompartmentalization within the host cell. Liquid–liquid phase …

Abstract α‐Synuclein (α‐syn) is an intrinsically disordered protein (IDP) that undergoes
liquid‐liquid phase separation (LLPS), fibrillation, and forms insoluble intracellular Lewy …

The phase separation of biomolecules has become the focus of intense research in the past
decade, with a growing body of research implicating this phenomenon in essentially all …

Eukaryotic cells have both membranous and membraneless organelles. While the formation
mechanism of membranous organelles is well understood, the formation mechanism of …

The flexible structure of an intrinsically disordered protein (IDP) is known to be perturbed by
salt concentrations, which can be understood by electrostatic screening on charged amino …

Colorectal cancer is one of the most common malignant tumors in the digestive system, and
its high incidence and metastasis rate make it a terrible killer that threatens human health. In …

Salts modulate the behavior of intrinsically disordered proteins (IDPs) and influence the
formation of membraneless organelles through liquid–liquid phase separation (LLPS). In …

The stability and physiological function of many biomolecular coacervates depend on the
structure and dynamics of intrinsically disordered proteins (IDPs) that typically contain a …

Linear and nonlinear dielectric responses of solutions of intrinsically disordered proteins
(IDPs) were analyzed by combining molecular dynamics simulations with formal theories. A …