Therapeutic applications of AS1411 aptamer, an update review
Nucleolin or C23, is one of the most abundant non-ribosomal phosphoproteins of nucleolus.
However, in several cancers, nucleolin is highly expressed both intracellularly and on the …
However, in several cancers, nucleolin is highly expressed both intracellularly and on the …
Recent development of aptamer conjugated chitosan nanoparticles as cancer therapeutics
There is a surge in demand for safe and targeted therapy against cancer as the conventional
treatment approach fails to reach the specific site. Chemotherapeutic agents are generally …
treatment approach fails to reach the specific site. Chemotherapeutic agents are generally …
Aptamer-based targeted drug delivery systems: current potential and challenges
F He, N Wen, D **ao, J Yan, H **ong… - Current medicinal …, 2020 - ingentaconnect.com
Aptamers are single-stranded DNA or RNA with 20-100 nucleotides in length that can
specifically bind to target molecules via formed three-dimensional structures. These …
specifically bind to target molecules via formed three-dimensional structures. These …
Ultrasensitive detection of aflatoxin B1 and its major metabolite aflatoxin M1 using aptasensors: A review
In regard to tremendous toxicological effects of aflatoxin B1 (AFB1) and its major metabolite
aflatoxin M1 (AFM1) on human health, quality assessment of food is of great importance. On …
aflatoxin M1 (AFM1) on human health, quality assessment of food is of great importance. On …
Smart AS1411-aptamer conjugated pegylated PAMAM dendrimer for the superior delivery of camptothecin to colon adenocarcinoma in vitro and in vivo
In the current study camptothecin-loaded pegylated PAMAM dendrimer were synthesized
and were functionalized with AS1411 anti-nucleolin aptamers for site-specific targeting …
and were functionalized with AS1411 anti-nucleolin aptamers for site-specific targeting …
Aptamer-conjugated PLGA nanoparticles for delivery and imaging of cancer therapeutic drugs
Most problems associated with chemotherapeutic agents involve non-specific cytotoxicity,
low intratumoral accumulation and drug resistance. Targeted drug delivery systems (TDDS) …
low intratumoral accumulation and drug resistance. Targeted drug delivery systems (TDDS) …
Aptamer-based ATP-responsive delivery systems for cancer diagnosis and treatment
In recent years, many stimuli-triggered drug delivery platforms have been designed to
deliver drugs accurately to specific sites and reduce their side effects, improving “on …
deliver drugs accurately to specific sites and reduce their side effects, improving “on …
Co-delivery of doxorubicin and aptamer against Forkhead box M1 using chitosan-gold nanoparticles coated with nucleolin aptamer for synergistic treatment of cancer …
Herein, a nanotherapeutic delivery method was presented for co-delivery of doxorubicin
(DOX) and aptamer against Forkhead box M1 (FOXM1 Apt) to cancer cells. Firstly, the …
(DOX) and aptamer against Forkhead box M1 (FOXM1 Apt) to cancer cells. Firstly, the …
Multivalent aptamer approach: designs, strategies, and applications
Z Wang, X Yang, NZ Lee, X Cao - Micromachines, 2022 - mdpi.com
Aptamers are short and single-stranded DNA or RNA molecules with highly programmable
structures that give them the ability to interact specifically with a large variety of targets …
structures that give them the ability to interact specifically with a large variety of targets …
Aptamer-based probes for cancer diagnostics and treatment
X Hu, D Zhang, Z Zeng, L Huang, X Lin, S Hong - Life, 2022 - mdpi.com
Aptamers are single-stranded DNA or RNA oligomers that have the ability to generate
unique and diverse tertiary structures that bind to cognate molecules with high specificity. In …
unique and diverse tertiary structures that bind to cognate molecules with high specificity. In …