The growing need for biologics to be administered subcutaneously and ocularly, coupled
with certain indications requiring high doses, has resulted in an increase in drug substance …

Biologic drugs are used to treat a variety of cancers and chronic diseases. While most of
these treatments are administered intravenously by trained healthcare professionals, a …

Self-assembly of proteins and inorganic nanoparticles into terminal assemblies makes
possible a large family of uniformly sized hybrid colloids. These particles can be compared …

Freezing of protein solutions perturbs protein conformation, potentially leading to aggregate
formation during long-term storage in the frozen state. Macroscopic protein concentration …

Despite widespread vaccination, pertussis rates are rising in industrialized countries and
remain high worldwide. With no specific therapeutics to treat disease, pertussis continues to …

The climate change is significantly evolving novel microbes in the environment. In addition,
nanoscience is advancing promptly to provide environmentally friendly engineering …

Protein and peptide biopharmaceuticals have had a major impact on the treatment of a
number of diseases. There is a growing interest in overcoming some of the challenges …

To further advance a subcutaneous injection of monoclonal antibodies (mAbs) at elevated
concentrations, novel concepts are needed to lower the viscosity. The addition of high …

In this report, we have designed a dual responsive disposable electrode for the enumeration
of Escherichia coli K12 (E. coli K12). The immunomagnetic separation strategy provided …

Aggregation of therapeutic proteins is a major concern as aggregates lower the yield and
can impact the efficacy of the drug as well as the patient's safety. It can occur in all …